2,2,2-Trichloro-1-[4-(2-fluorobenzoyl)-1H-pyrrol-2-yl]ethan-1-one CAS 338403-88-6
| CAS No. | 338403-88-6 |
| Molecular Formula | C13H7Cl3FNO2 |
| Molecular Weight | 334.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,2,2-Trichloro-1-[4-(2-fluorobenzoyl)-1H-pyrrol-2-yl]ethan-1-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,2,2-Trichloro-1-[4-(2-fluorobenzoyl)-1H-pyrrol-2-yl]ethan-1-one (CAS 338403-88-6), molecular formula C13H7Cl3FNO2 and molecular weight 334.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,2,2-Trichloro-1-[4-(2-fluorobenzoyl)-1H-pyrrol-2-yl]ethan-1-one (C13H7Cl3FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,2,2-Trichloro-1-[4-(2-fluorobenzoyl)-1H-pyrrol-2-yl]ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H7Cl3FNO2 |
| Molecular Weight | 334.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trichloro Standards
- 2,2,2-Trichloro-1-(4-(4-fluorobenzoyl)-1H-pyrrol-2-yl)ethan-1-one (CAS 453557-67-0)
- Ethyl 4,5,7-trichloro-8-methoxyquinoline-3-carboxylate (CAS 648897-23-8)
- 3,3,7-Trichloro-2-oxoindoline-5-sulfonyl chloride (CAS 753482-71-2)
- 2,4,6-Trichloro-p-terphenyl (CAS 57346-61-9)
- 2,2,2-Trichloro-1-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)ethanone (CAS 259099-55-3)
- Trichloro-3-methaphos (CAS 2633-54-7)
- 2,4,6-Trichloro-N-(3-methoxyphenyl)pyrimidine-5-carboxamide (CAS 87847-99-2)
- 4,6,7-Trichloro-2-(pyrimidin-2-ylamino)-2,3-dihydrobenzofuran-5-ol (CAS 354552-50-4)
Recommended Standards
- 4-Chloro-2-iodo-3-methylthieno[2,3-b]pyridine-5-carbonitrile (CAS 930293-15-5)
- Domiphen-API (CAS 13900-14-6)
- N1-(11-(Trimethoxysilyl)undecyl)ethane-1,2-diamine (CAS 121772-92-7)
- 2,5-Bis(1,1,3,3-tetramethylbutyl)hydroquinone (CAS 903-19-5)
- 2-Amino-N-ethyl-N-(4-methoxybenzyl)acetamide (CAS 1182923-38-1)
- 4-Chloro-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 1258650-41-7)
- 4,5-Dichloro-2-hydroxybenzamide (CAS 100948-82-1)
- N-Methylcytisine (CAS 1609401-32-2)
- (R)-4-(3-Fluoropyrrolidin-1-yl)piperidine (CAS 929632-65-5)
- 2-(4-hydroxyphenoxy)acetamide (CAS 22446-14-6)
- Etoposide EP Impurity R (CAS 149839-65-6)
- 2,3-Difluoro-1-(hexyloxy)-4-methylbenzene (CAS 2635937-37-8)
- 1-[3-(Pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methanamine (CAS 857653-92-0)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
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