(E)-6-(4-chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl) oxime CAS 338404-54-9
| CAS No. | 338404-54-9 |
| Molecular Formula | C19H12Cl3N3OS |
| Molecular Weight | 436.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-6-(4-chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl) oxime.
(E)-6-(4-chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl) oxime (CAS 338404-54-9), molecular formula C19H12Cl3N3OS and molecular weight 436.74 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-6-(4-chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl) oxime (C19H12Cl3N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-6-(4-chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl) oxime meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H12Cl3N3OS |
| Molecular Weight | 436.74 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- (E)-{[6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene}[(2,4-dichlorophenyl)methoxy]amine (CAS 338404-55-0)
- 6-(4-Chlorophenyl)-2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338403-85-3)
- (5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)(morpholino)methanone (CAS 158939-84-5)
- 4-[5-(4-Chlorophenyl)-1-(2,5-dichlorophenyl)-1H-pyrazole-3-carbonyl]morpholine (CAS 477712-08-6)
- 4-[5-(4-Chlorophenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carbonyl]morpholine (CAS 477713-35-2)
- (Z)-{2-[(4-chlorophenyl)sulfanyl]-1-phenylethylidene}[(2,4-dichlorophenyl)methoxy]amine (CAS 344268-48-0)
- 5-(4-Chlorophenyl)-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylic acid (CAS 321392-14-7)
- 2-(N-(4-chlorophenyl)phenylsulfonamido)-N-(3,4-difluorophenyl)acetamide (CAS 337922-48-2)
Recommended Standards
- 2-Phenyl-N-(2,2,2-trichloro-1-((4-sulfamoylphenyl)amino)ethyl)acetamide (CAS 301816-70-6)
- N-(2-{[2,5-bis(2,2,2-trifluoroethoxy)phenyl]formamido}ethyl)-2-chloroacetamide (CAS 338404-61-8)
- 5-[2-(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)vinyl]-3-[3,5-di(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 648410-32-6)
- Thioctic Acid Impurity 7 (CAS CATO-C4X-15187)
- 5-Phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one (CAS 29274-13-3)
- ZL6T4Y1XP8 7784-09-0 Silver phosphate Silver orthophosphate Phosphoric acid silver salt (1:3) Trisilver phosphate Phosphoric acid, silver(1+) salt (1:3) Phosphoric acid, trisilver(1+) salt EINECS 232-049-0 Silver orthophosphate (Ag3PO4) Silver phosphate (Ag3PO4) Trisilver(1+) orthophosphate Trisilver(1+) phosphate UNII-ZL6T4Y1XP8 (CAS 7784-09-0)
- (E)-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methylidene)[(2,4-dichlorophenyl)methoxy]amine (CAS 477851-88-0)
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- Acetyl-(Leu28ยท31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
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