(E)-{[6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene}[(2,4-dichlorophenyl)methoxy]amine CAS 338404-55-0
| CAS No. | 338404-55-0 |
| Molecular Formula | C19H12Cl3N3OS |
| Molecular Weight | 436.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-{[6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene}[(2,4-dichlorophenyl)methoxy]amine (CAS 338404-55-0) is a high-purity analytical reference standard with the molecular formula C19H12Cl3N3OS and a molecular weight of 436.74 g/mol.
The molecular framework of (E)-{[6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene}[(2,4-dichlorophenyl)methoxy]amine (C19H12Cl3N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-{[6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene}[(2,4-dichlorophenyl)methoxy]amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H12Cl3N3OS |
| Molecular Weight | 436.74 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- (E)-6-(4-chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl) oxime (CAS 338404-54-9)
- 6-(4-Chlorophenyl)-2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338403-85-3)
- (5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)(morpholino)methanone (CAS 158939-84-5)
- 4-[5-(4-Chlorophenyl)-1-(2,5-dichlorophenyl)-1H-pyrazole-3-carbonyl]morpholine (CAS 477712-08-6)
- 4-[5-(4-Chlorophenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carbonyl]morpholine (CAS 477713-35-2)
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- 5-(4-Chlorophenyl)-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylic acid (CAS 321392-14-7)
- 2-(N-(4-chlorophenyl)phenylsulfonamido)-N-(3,4-difluorophenyl)acetamide (CAS 337922-48-2)
Recommended Standards
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