Methyl 1-(4-chlorophenyl)-6-oxo-4-[3-(trifluoromethyl)phenoxy]-1,6-dihydropyridazine-3-carboxylate CAS 338405-39-3
| CAS No. | 338405-39-3 |
| Molecular Formula | C19H12ClF3N2O4 |
| Molecular Weight | 424.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Methyl 1-(4-chlorophenyl)-6-oxo-4-[3-(trifluoromethyl)phenoxy]-1,6-dihydropyridazine-3-carboxylate (CAS 338405-39-3), a certified reference material (molecular formula C19H12ClF3N2O4, MW 424.76 g/mol) for analytical method development and quality control.
Methyl 1-(4-chlorophenyl)-6-oxo-4-[3-(trifluoromethyl)phenoxy]-1,6-dihydropyridazine-3-carboxylate (C19H12ClF3N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 1-(4-chlorophenyl)-6-oxo-4-[3-(trifluoromethyl)phenoxy]-1,6-dihydropyridazine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H12ClF3N2O4 |
| Molecular Weight | 424.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 1-[2-(2-chlorophenyl)-2-oxoethyl]-3-[3-(trifluoromethyl)benzyl]-1H-imidazole-2,4,5(3H)-trione 303986-59-6 KS-00002ZQN (CAS 303986-59-6)
- 6-(2-Chlorophenyl)-2-(naphthalen-2-yloxy)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 478049-44-4)
- 6-(3-Chlorophenyl)-2-(naphthalen-2-yloxy)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-36-3)
- 6-(4-Chlorophenyl)-2-(naphthalen-2-yloxy)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-46-5)
- 2-((2-(4-Chlorophenyl)-2-oxoethyl)thio)-3-phenyl-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 692287-35-7)
- 4-((4-Chlorophenyl)sulfonyl)-2-(2-fluorophenyl)-N-(3-methoxypropyl)oxazol-5-amine (CAS 823829-89-6)
- 1-(4-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitrophenyl)ethan-1-one (CAS 1030856-24-6)
- 2-{[(4-chlorophenyl)carbamoyl]amino}-2-phenylethyl 4-methoxybenzoate (CAS 343373-26-2)
Recommended Standards
- 4-((5-Chloro-6-oxo-1-(3-(trifluoromethyl)phenyl)-1,6-dihydropyridazin-4-yl)oxy)-3-methoxybenzaldehyde (CAS 881580-69-4)
- tert-Butyl(3-(4-bromophenyl)-2-(4-chlorophenyl)propyl)carbamate (CAS 1065075-71-9)
- 2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-5-(trifluoromethyl)aniline (CAS 338773-00-5)
- 2-Methyl-4,6-Bis(Octylsulfanylmethyl)Phenol (CAS 110553-27-0)
- 8-Bromo-5,5,7,7-tetramethyl-4-nitro-1,5,6,7-tetrahydrocyclopenta[f]indazole (CAS 1227955-14-7)
- 2-Butyl-4-chloro-6-ethylthieno[2,3-d]pyrimidine (CAS 1515489-90-3)
- 6-Isopropyl-7-methoxy-1H-indole (CAS 1167055-81-3)
- Methyl 5-Hydroxyisoxazolo[4,5-b]pyrazine-3-carboxylate (CAS 1374986-04-5)
- 2-(3-Bromophenyl)-4,4,4-trifluorobutanoic acid (CAS 1508090-91-2)
- 2-(2-(Dimethylamino)ethoxy)-5-methylaniline (CAS 946715-60-2)
- Nordihydrocodeine (CAS 845-69-2)
- 7-Methyl-1H-indole-4-carboxylic acid (CAS 1082041-38-0)
- (Z)-Penta-2,4-dienal (CAS 37918-47-1)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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