3-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate CAS 338405-83-7
| CAS No. | 338405-83-7 |
| Molecular Formula | C16H15F3N2O5S |
| Molecular Weight | 404.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (C16H15F3N2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338405-83-7) is a high-purity analytical reference standard with the molecular formula C16H15F3N2O5S and a molecular weight of 404.36 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H15F3N2O5S |
| Molecular Weight | 404.36 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related trifluoromethoxy Standards
- 2-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338396-33-1)
- 4-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338396-20-6)
- N-{4-[4-(trifluoromethoxy)phenoxy]phenyl}-3-bromopropanamide (CAS 215519-06-5)
- 5-(3-(Trifluoromethoxy)phenyl)-1-(4-(trifluoromethyl)phenyl)pyrrolidine-2,3-dione (CAS 1031721-49-9)
- 4-(4-(Trifluoromethoxy)phenyl)-2-(4-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 343373-52-4)
- Ethyl 2-({5-[3-(trifluoromethoxy)benzamido]-1,3,4-thiadiazol-2-yl}sulfanyl)acetate (CAS 329699-49-2)
- 2-{[4-(trifluoromethoxy)phenyl]carbamoyl}thiophen-3-yl N,N-dimethylsulfamate (CAS 338794-49-3)
- Methyl 3-(5-{[4-(trifluoromethoxy)phenyl]carbamoyl}furan-2-yl)thiophene-2-carboxylate (CAS 320417-59-2)
Recommended Standards
- 4-{[4-(2-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfonyl}butanoic acid (CAS 443105-09-7)
- 2-((4-Bromophenyl)thio)-N-(4-cyclohexylphenyl)acetamide (CAS 212074-96-9)
- Enpiroline (CAS 66364-73-6)
- N-(4-(2,5-dimethyl-3-(2,2,2-trifluoroacetyl)-1H-pyrrol-1-yl)phenyl)-2-fluorobenzamide (CAS 866156-48-1)
- 3-Amino-2-[(4-ethoxyphenyl)methyl]propanamide (CAS 1038293-54-7)
- 4-Chloro-3-nitro-N-propylbenzamide (CAS 321531-57-1)
- tert-butyl (R)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((E)-1-phenylprop-1-en-2-yl)amino)propyl)pyrrolidine-1-carboxylate (CAS CATO-CPTD789007)
- 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one (CAS 139256-06-7)
- 2-Chloro-n-(3-cyclopropyl-1-phenyl-1h-pyrazol-5-yl)acetamide (CAS 649701-41-7)
- N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-((4-methoxybenzyl)oxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)benzamide (CAS 80015-56-1)
- 2,6-Dimethyl-3,6-dihydro-2H-pyran-4-yl trifluoromethanesulfonate (CAS 195817-69-7)
- 2-(2-((4-Fluorophenyl)sulfonamido)thiazol-4-yl)acetic acid (CAS 926202-75-7)
- 3,4-Dihydro-4-methyl-3-oxo-2H-1,4-benzothiazine-7-sulphonyl chloride 1,1-dioxide (CAS 874840-15-0)
- Semaglutide impurity 38 (CAS CATO-C4X-222638)
Why CATO?
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