2-{[4-(trifluoromethoxy)phenyl]carbamoyl}thiophen-3-yl N,N-dimethylsulfamate CAS 338794-49-3
| CAS No. | 338794-49-3 |
| Molecular Formula | C14H13F3N2O5S2 |
| Molecular Weight | 410.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 410.39 g/mol gives 2-{[4-(trifluoromethoxy)phenyl]carbamoyl}thiophen-3-yl N,N-dimethylsulfamate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-{[4-(trifluoromethoxy)phenyl]carbamoyl}thiophen-3-yl N,N-dimethylsulfamate (CAS 338794-49-3), a certified reference material (molecular formula C14H13F3N2O5S2, MW 410.39 g/mol) for analytical method development and quality control.
The molecular framework of 2-{[4-(trifluoromethoxy)phenyl]carbamoyl}thiophen-3-yl N,N-dimethylsulfamate (C14H13F3N2O5S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-{[4-(trifluoromethoxy)phenyl]carbamoyl}thiophen-3-yl N,N-dimethylsulfamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13F3N2O5S2 |
| Molecular Weight | 410.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related trifluoromethoxy Standards
- Methyl 3-(5-{[4-(trifluoromethoxy)phenyl]carbamoyl}furan-2-yl)thiophene-2-carboxylate (CAS 320417-59-2)
- Ethyl 2-({5-[3-(trifluoromethoxy)benzamido]-1,3,4-thiadiazol-2-yl}sulfanyl)acetate (CAS 329699-49-2)
- 2-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338396-33-1)
- 3-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338405-83-7)
- 4-{[4-(trifluoromethoxy)phenyl]carbamoyl}phenyl N,N-dimethylsulfamate (CAS 338396-20-6)
- N-{4-[4-(trifluoromethoxy)phenoxy]phenyl}-3-bromopropanamide (CAS 215519-06-5)
- 5-(3-(Trifluoromethoxy)phenyl)-1-(4-(trifluoromethyl)phenyl)pyrrolidine-2,3-dione (CAS 1031721-49-9)
- 4-(4-(Trifluoromethoxy)phenyl)-2-(4-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 343373-52-4)
Recommended Standards
- 1-(Furan-2-ylmethyl)-5-oxo-N-(2-propoxy-5-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide (CAS 870760-17-1)
- 2-bromo LSD (CAS 478-84-2)
- 7-(((4-Methylpyrimidin-2-yl)amino)(4-(trifluoromethyl)phenyl)methyl)quinolin-8-ol (CAS 1351140-16-3)
- 3-[(3R,4R)-3-(Hydroxymethyl)-8-methoxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3-methyl-1-[3-(trifluoromethyl)phenyl]urea (CAS 324009-19-0)
- [4-(Aminomethyl)bicyclo[2.2.2]oct-1-yl]methanol (CAS 916304-06-8)
- 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carbothioamide (CAS 175204-42-9)
- 3-(Chloromethyl)-6-isopropylquinolin-2(1H)-one (CAS 1017347-07-7)
- 3-(2,4-Dichlorophenyl)-1-(2,4-difluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618383-10-1)
- 2 - (4 - Methoxy - phenyl) - pyrrolidine 2-(4-methoxyphenyl)pyrrolidine 2-[4-(methoxy)phenyl]pyrrolidine 74190-66-2 methyl 4-(2-pyrrolidinyl)phenyl ether pyrrolidine, 2-(4-methoxyphenyl)- (CAS 74190-66-2)
- Canagliflozin Impurity 15 (CAS 1830346-16-1)
- N-(4-Amino-2-methylphenyl)-4-methoxybenzamide (CAS 869953-47-9)
- 863248-36-6 (2-Fluoro-5-propoxyphenyl)boronic acid DTXSID10584402 (CAS 863248-36-6)
- Gc-6506-wettable powder granules (CAS 3254-63-5)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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