N-(2,4-difluorophenyl)-6-(1H-imidazol-1-yl)nicotinamide CAS 338405-89-3
| CAS No. | 338405-89-3 |
| Molecular Formula | C15H10F2N4O |
| Molecular Weight | 300.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-(2,4-difluorophenyl)-6-(1H-imidazol-1-yl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies N-(2,4-difluorophenyl)-6-(1H-imidazol-1-yl)nicotinamide (CAS 338405-89-3), a certified reference material (molecular formula C15H10F2N4O, MW 300.26 g/mol) for analytical method development and quality control.
The molecular framework of N-(2,4-difluorophenyl)-6-(1H-imidazol-1-yl)nicotinamide (C15H10F2N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H10F2N4O |
| Molecular Weight | 300.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
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Recommended Standards
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- Rhamnocitrin (CAS 569-92-6)
- 2-(3-Tert-butylphenoxy)propanoic acid (CAS 50397-71-2)
- Trinaphtho[1,2,3,4-fgh:1',2',3',4'-pqr:1'',2'',3'',4''-za1b1]trinaphthylene (CAS 1065-80-1)
- Lariciresinol-4,4'-dimethyl ether-9-acetate (CAS 73354-15-1)
- 2-(4-Chlorobenzyl)-6-nitro-1H-benzo[d]imidazole (CAS 111500-52-8)
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