1-(2,4-Difluorophenyl)-3-phenyl-1H-pyrazole-5-carboxylic acid CAS 618101-96-5
| CAS No. | 618101-96-5 |
| Molecular Formula | C16H10F2N2O2 |
| Molecular Weight | 300.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2,4-Difluorophenyl)-3-phenyl-1H-pyrazole-5-carboxylic acid (C16H10F2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(2,4-Difluorophenyl)-3-phenyl-1H-pyrazole-5-carboxylic acid (CAS 618101-96-5) is a high-purity analytical reference standard with the molecular formula C16H10F2N2O2 and a molecular weight of 300.26 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2,4-Difluorophenyl)-3-phenyl-1H-pyrazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10F2N2O2 |
| Molecular Weight | 300.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorophenyl Standards
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- N-(2,4-Difluorophenyl)-6-(1H-pyrazol-1-yl)pyridine-3-carboxamide (CAS 400078-68-4)
- N-(3,5-Difluorophenyl)-2-hydrazinylpyridine-3-sulfonamide (CAS 1155081-22-3)
- 1-(3,4-Difluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898778-64-8)
- 1-(3,5-Difluorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898778-66-0)
- N4-(2,4-Difluorophenyl)-N2-isobutyl-L-asparagine (CAS 1048010-11-2)
- (1-(2,4-Difluorophenyl)-3-(p-tolyl)-1H-pyrazol-4-yl)methanol (CAS 618383-22-5)
Recommended Standards
- (2S,3R,4S,5S,6R)-2-(2H-1,3-benzodioxol-4-yloxy)-6-(hydroxymethyl)oxane-3,4,5-triol (CAS 1955474-56-2)
- 1-(2-Fluorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-83-3)
- N-Biotinyl-4,7,10-trioxa-1,13-tridecanediamine, 96% (CAS 183896-00-6)
- 1-(4-Hydroxybenzoyl)glucose (CAS 25545-07-7)
- N-(+)-Biotinyl-3-aminopropylammonium trifluoroacetate (CAS 244760-26-7)
- 3-Cyanoumbelliferone (CAS 19088-73-4)
- 3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)aniline hydrochloride (CAS 850567-43-0)
- 8-Bromo-7-(2-methoxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CAS 141794-40-3)
- (3-Amino-6-chloropyridin-2-yl)methanol (CAS 1206454-48-9)
- 1-{[3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}piperazine hydrochloride 1417566-86-9 (CAS 1417566-86-9)
- 2-Amino-5-methyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1214901-53-7)
- 4-Hydroxypiperidine-2,2,6,6-d4 (CAS 1014695-51-2)
- Methyl 2-(4-bromo-2,3-difluorophenyl)acetate (CAS 1807040-78-3)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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