3-((4-Chlorophenyl)sulfonyl)-5-(trifluoromethyl)picolinonitrile CAS 338406-75-0
| CAS No. | 338406-75-0 |
| Molecular Formula | C13H6ClF3N2O2S |
| Molecular Weight | 346.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((4-Chlorophenyl)sulfonyl)-5-(trifluoromethyl)picolinonitrile (CAS 338406-75-0), molecular formula C13H6ClF3N2O2S and molecular weight 346.71 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-((4-Chlorophenyl)sulfonyl)-5-(trifluoromethyl)picolinonitrile (C13H6ClF3N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 346.71 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-((4-Chlorophenyl)sulfonyl)-5-(trifluoromethyl)picolinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H6ClF3N2O2S |
| Molecular Weight | 346.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(5-fluoro-2-methylphenyl)acetamide (CAS 439107-80-9)
- 2-Chloro-4-(methylsulfonyl)-3-((2,2,2-trifluoroethoxy)methyl)benzoic acid (CAS 120100-77-8)
- Coumaphos-oxon (CAS 321-54-0)
- ((2R,3R,4R,5R)-3-Acetoxy-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate (CAS 10190-39-3)
- (S)-(-)-N-[1-(Hydroxymethyl)-2-phenylethyl]-4-methylbenzenesulfonamide (S)-N-(1-hydroxy-3-phenylpropan-2-yl)-4-methylbenzenesulfonamide 82495-70-3 (CAS 82495-70-3)
- ethyl 5-(4-chlorophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylate (CAS 1283530-38-0)
- [1,1'-Biphenyl]-4-yl(4-(thiophen-2-yl)piperidin-1-yl)methanone (CAS 1396803-35-2)
- Elagolix Impurity 67 (CAS CATO-C4X-206867)
- 2-bromo-5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazole (CAS 1344330-79-5)
- 4-Fluoro-5-morpholino-2-nitrobenzoic Acid (CAS 1033778-62-9)
- tert-Butyl (3-chloro-4,5-bis(trifluoromethyl)phenyl)carbamate (CAS 2803283-48-7)
- Methyl 2-(3'-amino-[1,1'-biphenyl]-4-yl)acetate (CAS 1123168-99-9)
- 6β-Hydroxy Estrone (CAS 1229-25-0)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
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