2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(5-fluoro-2-methylphenyl)acetamide CAS 439107-80-9

Purity 97%+In StockPharmaceutical Standards
CAS No.439107-80-9
Molecular FormulaC15H11ClF4N2O
Molecular Weight346.71 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(5-fluoro-2-methylphenyl)acetamide CAS 439107-80-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 346.71 g/mol gives 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(5-fluoro-2-methylphenyl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(5-fluoro-2-methylphenyl)acetamide (CAS 439107-80-9) is a high-purity analytical reference standard with the molecular formula C15H11ClF4N2O and a molecular weight of 346.71 g/mol.

The molecular framework of 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(5-fluoro-2-methylphenyl)acetamide (C15H11ClF4N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(5-fluoro-2-methylphenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H11ClF4N2O
Molecular Weight346.71 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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