4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanamide CAS 338406-95-4
| CAS No. | 338406-95-4 |
| Molecular Formula | C16H14ClF3N2O3S |
| Molecular Weight | 406.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanamide (CAS 338406-95-4), molecular formula C16H14ClF3N2O3S and molecular weight 406.81 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanamide (C16H14ClF3N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClF3N2O3S |
| Molecular Weight | 406.81 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Benzenesulfonyl Standards
- 5-(Benzenesulfonyl)-4-(2-chlorophenyl)-2-phenylpyrimidine (CAS 339107-55-0)
- 7-(Benzenesulfonyl)-6-bromo-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine (CAS 1131992-26-1)
- 1-(Benzenesulfonyl)-N'-[(1E)-(4-chlorophenyl)methylidene]piperidine-4-carbohydrazide (CAS 478030-62-5)
- 4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanoic acid (CAS 338407-19-5)
- 5-(Benzenesulfonyl)-4-(4-chlorophenyl)-2-(pyridin-2-yl)pyrimidine (CAS 339107-25-4)
- (2E)-2-(Benzenesulfonyl)-3-[6-(4-methylphenyl)imidazo[2,1-b][1,3]thiazol-5-yl]prop-2-enenitrile (CAS 691883-96-2)
- Methyl 4-[4-(benzenesulfonyl)piperazin-1-yl]-3-nitrobenzoate (CAS 478246-37-6)
- 5-(Benzenesulfonyl)-4-(3,4-dichlorophenyl)-N,N-dimethylpyrimidin-2-amine (CAS 339107-76-5)
Recommended Standards
- 3-Chloro-2-[4-(pyrrolidine-1-sulfonyl)phenoxy]-5-(trifluoromethyl)pyridine (CAS 344278-02-0)
- 5-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-3-yl)-2-phenylthiazole (CAS 318255-90-2)
- (2E)-3-(3-Chloro-1-benzothiophen-2-yl)-2-cyano-N-[3-(trifluoromethyl)phenyl]prop-2-enamide (CAS 477868-43-2)
- 5-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]-3-[3-(trifluoromethyl)phenyl]-1,2-oxazole (CAS 400079-70-1)
- 6-Chloro-2-cyclopentyl-4-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridine (CAS 1018127-74-6)
- 4-((3-Methylbutan-2-yl)amino)benzonitrile (CAS 1019613-31-0)
- 7-Bromo-2-chloro-3-methylquinazolin-4(3H)-one (CAS 1404480-64-3)
- N-benzyl-2-((5-(4-ethoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 763126-26-7)
- 3-(o-Tolyl)-4,5-dihydro-1H-pyrazole (CAS 361442-92-4)
- 3’-Bromo-5’-chloro-2’-hydroxyacetophenone (CAS 59443-15-1)
- 3-Chloro-5-phenylisothiazole-4-carbonitrile (CAS 28989-23-3)
- 3-Chloro-4,5-bis(trifluoromethyl)aniline (CAS 1807224-55-0)
- (D)-PPA 1 (CAS 1620813-53-7)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com