3-Chloro-2-[4-(pyrrolidine-1-sulfonyl)phenoxy]-5-(trifluoromethyl)pyridine CAS 344278-02-0
| CAS No. | 344278-02-0 |
| Molecular Formula | C16H14ClF3N2O3S |
| Molecular Weight | 406.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-2-[4-(pyrrolidine-1-sulfonyl)phenoxy]-5-(trifluoromethyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-2-[4-(pyrrolidine-1-sulfonyl)phenoxy]-5-(trifluoromethyl)pyridine (CAS 344278-02-0) is a high-purity analytical reference standard with the molecular formula C16H14ClF3N2O3S and a molecular weight of 406.81 g/mol.
The molecular framework of 3-Chloro-2-[4-(pyrrolidine-1-sulfonyl)phenoxy]-5-(trifluoromethyl)pyridine (C16H14ClF3N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-2-[4-(pyrrolidine-1-sulfonyl)phenoxy]-5-(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClF3N2O3S |
| Molecular Weight | 406.81 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)benzo[d]thiazole (CAS 1023553-54-9)
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Recommended Standards
- 4-(Benzenesulfonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]butanamide (CAS 338406-95-4)
- 5-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]-3-[3-(trifluoromethyl)phenyl]-1,2-oxazole (CAS 400079-70-1)
- 2-(4-Chlorobenzenesulfonamido)-N-[3-(trifluoromethyl)phenyl]propanamide (CAS 1008261-45-7)
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- 3-(3-Methylphenyl)-5H-indeno[1,2-c]pyridazin-5-one (CAS 303148-06-3)
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- 5,6-Diaminoquinolin-2(1H)-one (CAS 1378260-94-6)
- thiazolo[5,4-d]pyrimidine (CAS 273-86-9)
- 1-(2,4,6-Trichlorophenyl)ethanone (CAS 52120-00-0)
- 3-(4-chloro-3-fluorophenoxy)propanoic acid (CAS 1499920-96-5)
- 551936-17-5 3JX85UOO24 AIM-102 UNII-3JX85UOO24 (4R)-4-(((2R)-2-Amino-3-cyclohexyl-propanoyl)amino)-5-(carboxymethylamino)-5-oxo-pentanoic acid D-Cyclohexylalanine-D-glutamic-glycine tripeptide Glycine, 3-cyclohexyl-D-alanyl-D-alpha-glutamyl- (CAS 551936-17-5)
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