2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[3-(trifluoromethyl)phenyl]acetamide CAS 338407-32-2
| CAS No. | 338407-32-2 |
| Molecular Formula | C15H9ClF6N2O |
| Molecular Weight | 382.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 382.69 g/mol gives 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[3-(trifluoromethyl)phenyl]acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[3-(trifluoromethyl)phenyl]acetamide (CAS 338407-32-2), molecular formula C15H9ClF6N2O and molecular weight 382.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[3-(trifluoromethyl)phenyl]acetamide (C15H9ClF6N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-[3-(trifluoromethyl)phenyl]acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H9ClF6N2O |
| Molecular Weight | 382.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea (CAS 370-51-4)
- 3-(2-Chloro-6-fluorophenyl)-8-(trifluoromethyl)pyrido[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine (CAS 338420-45-4)
- 3-Chloro-N-[5-(5-(trifluoromethyl)pyridin-2-yl)--[1,2,4]oxadiazol-3-ylmethyl]benzamide (CAS 1311278-49-5)
- 4-Chloro-1-methyl-2-phenyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-2,3-dihydro-1H-pyrazol-3-one (CAS 946387-08-2)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-morpholino-2-(pyridin-2-yl)acetonitrile (CAS 339011-88-0)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-morpholino-2-(pyridin-4-yl)acetonitrile (CAS 339099-85-3)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(2,6-dimethylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860789-14-6)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetyl)piperidine-4-carboxylic acid (CAS 731793-33-2)
Recommended Standards
- 64415-14-1 11PW1H7SFJ 4-Phenyl-5-tetradecyl-2-thiazolamine 4-Phenyl-5-tetradecylthiazol-2-amine EINECS 264-881-5 NSC 108241 UNII-11PW1H7SFJ (CAS 64415-14-1)
- N-(3-Bromophenyl)-4-(4-chloro-3-methylphenoxy)butanamide (CAS 691391-60-3)
- 3,5-bis(trifluoromethyl)phenyl 4-(chloromethyl)benzoate (CAS 680579-24-2)
- Profenofos D3 (CAS 2140327-42-8)
- 2-(((Benzyloxy)carbonyl)amino)-5-bromobenzoic acid (CAS 778601-73-3)
- 2,5-Dimethyl-1-(pyridin-3-ylmethyl)-1H-pyrrole-3-carbaldehyde (CAS 878424-30-7)
- (R)-2-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]Decane-3-carboxylic acid (CAS 2306253-96-1)
- 2-((Diethylamino)methyl)aniline dihydrochloride (CAS 1185297-71-5)
- Atrasentan Impurity 27 (CAS 1058401-87-8)
- Metoclopramide Impurity 38 (CAS CATO-C4X-141538)
- (E)-4-(2-(thiophen-2-yl)vinyl)-8-(trifluoromethoxy)-2,3-dihydrothieno[3,2-c]quinoline (CAS 866133-43-9)
- 2-(4-Chlorophenyl)-5-(methylsulfonyl)-1,3,4-thiadiazole (CAS 63857-87-4)
- 4-Chloro-3-difluoromethyl-5-(4-methoxyphenyl)pyrazole (CAS 1029635-77-5)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
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