(E)-4-(2-(thiophen-2-yl)vinyl)-8-(trifluoromethoxy)-2,3-dihydrothieno[3,2-c]quinoline CAS 866133-43-9
| CAS No. | 866133-43-9 |
| Molecular Formula | C18H12F3NOS2 |
| Molecular Weight | 379.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(E)-4-(2-(thiophen-2-yl)vinyl)-8-(trifluoromethoxy)-2,3-dihydrothieno[3,2-c]quinoline (CAS 866133-43-9), molecular formula C18H12F3NOS2 and molecular weight 379.42 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-4-(2-(thiophen-2-yl)vinyl)-8-(trifluoromethoxy)-2,3-dihydrothieno[3,2-c]quinoline (C18H12F3NOS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H12F3NOS2 |
| Molecular Weight | 379.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
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- N-(4-((6-Methyl-3-thioxo-2,3-dihydro-1,2,4-triazin-5-yl)amino)phenyl)acetamide (CAS 942887-11-8)
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