3-Chloro-2-[2-(1H-1,2,4-triazol-3-yl)-1H-pyrrol-1-yl]-5-(trifluoromethyl)pyridine CAS 338407-41-3
| CAS No. | 338407-41-3 |
| Molecular Formula | C12H7ClF3N5 |
| Molecular Weight | 313.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-2-[2-(1H-1,2,4-triazol-3-yl)-1H-pyrrol-1-yl]-5-(trifluoromethyl)pyridine (CAS 338407-41-3), molecular formula C12H7ClF3N5 and molecular weight 313.67 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 3-Chloro-2-[2-(1H-1,2,4-triazol-3-yl)-1H-pyrrol-1-yl]-5-(trifluoromethyl)pyridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 313.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF3N5 |
| Molecular Weight | 313.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 7-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1048383-29-4)
- 5-Chloro-3-(3-(trifluoromethoxy)phenyl)pyrazolo[1,5-a]pyrimidine (CAS 1361951-79-2)
- 3-Chloro-1'-methyl-6'-oxo-5-(trifluoromethyl)-1',6'-dihydro-[2,3'-bipyridine]-5'-carbonitrile (CAS 1823183-08-9)
- 3-Chloro-6'-methoxy-5-(trifluoromethyl)-[2,3'-bipyridine]-5'-carbonitrile (CAS 339012-08-7)
- 6-Chloro-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine (CAS 928337-00-2)
- (E)-5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde O-(2,6-difluorobenzoyl) oxime (CAS 956797-71-0)
- 2-(2-Chloro-5-nitrobenzylidene)-1H-indene-1,3(2H)-dione (CAS 862649-84-1)
- 1094289-71-0 2-Chloro-2-phenyl-N-[2-(trifluoromethyl)phenyl]acetamide MFCD13356933 (CAS 1094289-71-0)
Recommended Standards
- 2-(3-(1H-pyrrol-1-yl)-1H-1,2,4-triazol-1-yl)-3-chloro-5-(trifluoromethyl)pyridine (CAS 303144-56-1)
- Dimethyl 1-(3-chloro-4-fluorophenyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 252654-10-7)
- Flucloxacillin RC 6 (CAS 1797824-55-5)
- 2-(2,2,2-Trifluoroacetyl)isoindoline-5-sulfonyl chloride (CAS 1374655-15-8)
- 2-Oleoyl Glycerol-d5 (CAS 946524-37-4)
- 2-Bromo-3-cyclopropoxy-4-nitropyridine (CAS 1243365-48-1)
- 1-(3-Methoxyphenyl)-2-methylpropan-2-ol (CAS 23037-39-0)
- 2-Cyclopropoxy-5-nitrobenzonitrile (CAS 1243465-67-9)
- 3-Cyclopropoxy-5-iodo-2-(methylthio)pyridine (CAS 1243353-72-1)
- 4-Amino-2,2,6,6-tetramethylpiperidinyloxy (CAS 14691-88-4)
- 3-Amino-4-methoxybutanoic acid (CAS 824424-72-8)
- 1-(2,4-Dichlorophenyl)-1h-pyrazol-4-amine (CAS 14044-29-2)
- (E)-[(2-{[(4-chlorophenyl)methyl]sulfanyl}quinolin-3-yl)methylidene]amino 3-methylbenzoate (CAS 478079-35-5)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
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