3-((4-Aminophenyl)thio)-5-(trifluoromethyl)picolinonitrile CAS 338407-42-4
| CAS No. | 338407-42-4 |
| Molecular Formula | C13H8F3N3S |
| Molecular Weight | 295.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-((4-Aminophenyl)thio)-5-(trifluoromethyl)picolinonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-((4-Aminophenyl)thio)-5-(trifluoromethyl)picolinonitrile (CAS 338407-42-4), molecular formula C13H8F3N3S and molecular weight 295.28 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-((4-Aminophenyl)thio)-5-(trifluoromethyl)picolinonitrile (C13H8F3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 295.28 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-((4-Aminophenyl)thio)-5-(trifluoromethyl)picolinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8F3N3S |
| Molecular Weight | 295.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Aminophenyl Standards
- 3-((2-Aminophenyl)thio)-5-(trifluoromethyl)picolinonitrile (CAS 338396-88-6)
- 1-(3-aminophenyl)-3-[3-(trifluoromethyl)phenyl]urea (CAS 1041510-67-1)
- (S)-3-((2-Aminophenyl)amino)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 175211-38-8)
- N-(2-aminophenyl)-1-(2,2-dichlorocyclopropyl)methanesulfonamide (CAS 1146290-04-1)
- 2-(4-Aminophenyl)-1-(4-phenylpiperazin-1-yl)ethan-1-one (CAS 1016528-63-4)
- (4-(4-Aminophenyl)piperazin-1-yl)(o-tolyl)methanone (CAS 640759-17-7)
- (4-(4-Aminophenyl)piperazin-1-yl)(p-tolyl)methanone (CAS 262376-01-2)
- 3-[(4-Aminophenyl)thio]-N-(5-methyl-1,3,4-thiadiazol-2-yl)propanamide (CAS 931292-80-7)
Recommended Standards
- 4-(Prop-2-yn-1-ylsulfanyl)-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 338418-25-0)
- 2-(1H-Pyrrol-1-yl)-4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 860788-79-0)
- 4-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]phenol (CAS 880088-31-3)
- (4-Fluorophenyl)[6-(4-fluorophenyl)-3-pyridinyl]methanone (CAS 866135-75-3)
- Potassium (4-butylphenyl)trifluoroboranuide (CAS 1412414-09-5)
- tert-Butyl 2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate hydrochloride (CAS 1279861-05-0)
- 4-[(4-Piperidinylmethoxy)methyl]piperidine dihydrochloride (CAS 1211514-33-8)
- Crizotinib Impurity 58 (CAS CATO-C4X-102558)
- Fucα(1-6)GlcNAc (CAS 33639-80-4)
- Methyl 2-methylpyrrolidine-1-carboxylate (CAS 222178-82-7)
- (-)-Δ9-THC-D3 (CAS 81586-39-2)
- 2-Chloro-3-iodo-6-methylpyridine (CAS 1214372-51-6)
- (Z)-2-Bromo-3-(dimethylamino)acrylaldehyde (CAS 20591-60-0)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
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