4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)benzaldehyde CAS 338409-17-9
| CAS No. | 338409-17-9 |
| Molecular Formula | C19H19ClF3N3O2 |
| Molecular Weight | 413.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)benzaldehyde is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)benzaldehyde (CAS 338409-17-9), a certified reference material (molecular formula C19H19ClF3N3O2, MW 413.82 g/mol) for analytical method development and quality control.
The molecular framework of 4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)benzaldehyde (C19H19ClF3N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H19ClF3N3O2 |
| Molecular Weight | 413.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- 4-(5-Chloro-2-methylphenyl)-N-(4-(trifluoromethoxy)phenyl)piperazine-1-carboxamide (CAS 1023568-80-0)
- 2-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)benzaldehyde (CAS 338408-89-2)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(4-methoxyphenyl)piperazin-1-yl)ethan-1-one (CAS 692737-09-0)
- 3-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethoxy)benzaldehyde (CAS 338409-15-7)
- (S)-4-(1-(5-Chloro-2-(4-fluorophenoxy)-benzamido)ethyl)benzoic acid (CAS 847728-01-2)
- N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide (CAS 918505-84-7)
- (2E)-3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-N-[(4-fluorophenyl)methyl]prop-2-enamide (CAS 477870-76-1)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-3-(phenylthio)-1H-pyrrole-2,5-dione (CAS 338772-53-5)
Recommended Standards
- N-(4-((4-Chloropiperidin-1-yl)sulfonyl)phenyl)-5-nitrofuran-2-carboxamide (CAS 1523437-16-2)
- 2,4,6-Tris(bromofluoromethyl)-1,3,5-triazine (CAS 402-94-8)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 303091-71-6)
- 1-(2-Chloro-5-(trifluoromethyl)phenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrole (CAS 338749-72-7)
- 4-Amino-3-benzylbutanoic acid (CAS 30200-05-6)
- 2-Methyl-[1,1'-biphenyl]-4-carbaldehyde (CAS 1256468-34-4)
- 1-(2,4-Difluorophenyl)cyclobutanecarboxylic Acid (CAS 1260672-69-2)
- o-[(3-chlorophenyl)methyl]hydroxylamine (CAS 55418-31-0)
- 2,4,5-Trimethyl-N-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)benzenesulfonamide (CAS 1235072-31-7)
- tert-Butyl 2-((pyridin-2-ylthio)methyl)pyrrolidine-1-carboxylate (CAS 1353967-38-0)
- 2-Butoxy-5-methylpyridin-3-amine (CAS 1529165-65-8)
- 5-{[4-(trifluoromethoxy)phenyl]amino}-1,3,4-thiadiazole-2-thiol (CAS 883041-73-4)
- 3-[2-(sec-Butyl)-4-chlorophenoxy]azetidine (CAS 1220038-53-8)
- Brain Injury Derived Neurotrophic Peptide (H-3914.0001) (CAS 148330-12-5)
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