N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide CAS 918505-84-7
| CAS No. | 918505-84-7 |
| Molecular Formula | C17H14ClF2N3O3S |
| Molecular Weight | 413.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide.
CATO supplies N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide (CAS 918505-84-7), a certified reference material (molecular formula C17H14ClF2N3O3S, MW 413.83 g/mol) for analytical method development and quality control.
Structurally, N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide (C17H14ClF2N3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 413.83 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H14ClF2N3O3S |
| Molecular Weight | 413.83 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- (S)-4-(1-(5-Chloro-2-(4-fluorophenoxy)-benzamido)ethyl)benzoic acid (CAS 847728-01-2)
- 4-(5-Chloro-2-methylphenyl)-N-(4-(trifluoromethoxy)phenyl)piperazine-1-carboxamide (CAS 1023568-80-0)
- (2E)-3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-N-[(4-fluorophenyl)methyl]prop-2-enamide (CAS 477870-76-1)
- 1-(2-Chloro-5-(trifluoromethyl)phenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrole (CAS 338749-72-7)
- 2-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)benzaldehyde (CAS 338408-89-2)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(4-methoxyphenyl)piperazin-1-yl)ethan-1-one (CAS 692737-09-0)
- 3-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethoxy)benzaldehyde (CAS 338409-15-7)
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Recommended Standards
- N-(4-((4-Chloropiperidin-1-yl)sulfonyl)phenyl)-5-nitrofuran-2-carboxamide (CAS 1523437-16-2)
- 3-Amino-N-(2-chlorophenyl)-6-ethyl-5-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 664999-38-6)
- Sitafloxacin-D4 (CAS CATO-C4X-115552)
- 2,4,6-Tris(bromofluoromethyl)-1,3,5-triazine (CAS 402-94-8)
- 3-Methyl-2-methylene-2,3-dihydrobenzo[d]thiazole (CAS 23574-67-6)
- 5-bromo-4-oxo-pentanoic acid (CAS 14594-23-1)
- (4-((2-(Dimethylamino)ethyl)carbamoyl)phenyl)boronic acid (CAS 850689-33-7)
- 2-(2-Chloro-6-fluorophenyl)-2-(2-methylmorpholin-4-yl)ethan-1-amine (CAS 953728-13-7)
- Methyl 6-chloro-5-cyano-3,4-dimethylpicolinate (CAS 2581232-23-5)
- 2-Nitrobenzaldehyde-d (CAS 1020718-69-7)
- 2-(Trifluoromethyl)pyrimidine-5-carboximidamide (CAS 1511951-37-3)
- 4-(Dimethylcarbamoyl)-2-fluorophenylboronic Acid (CAS 874289-30-2)
- 2,3-Epoxybutanol (CAS 872-38-8)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
Why CATO?
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