4-(Tert-butyl)-N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)thiazol-2-amine CAS 338409-42-0
| CAS No. | 338409-42-0 |
| Molecular Formula | C13H13ClF3N3S |
| Molecular Weight | 335.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, 4-(Tert-butyl)-N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)thiazol-2-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 4-(Tert-butyl)-N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)thiazol-2-amine (CAS 338409-42-0), a certified reference material (molecular formula C13H13ClF3N3S, MW 335.78 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Tert-butyl)-N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13ClF3N3S |
| Molecular Weight | 335.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
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