6-Chloro-3-hydroxy-2-(2-methoxyphenyl)quinazolin-4(3H)-one CAS 338412-69-4
| CAS No. | 338412-69-4 |
| Molecular Formula | C15H11ClN2O3 |
| Molecular Weight | 302.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 302.71 g/mol gives 6-Chloro-3-hydroxy-2-(2-methoxyphenyl)quinazolin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6-Chloro-3-hydroxy-2-(2-methoxyphenyl)quinazolin-4(3H)-one (CAS 338412-69-4), a certified reference material (molecular formula C15H11ClN2O3, MW 302.71 g/mol) for analytical method development and quality control.
6-Chloro-3-hydroxy-2-(2-methoxyphenyl)quinazolin-4(3H)-one (C15H11ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-3-hydroxy-2-(2-methoxyphenyl)quinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11ClN2O3 |
| Molecular Weight | 302.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- Methyl 2-[4-(4-chlorophenyl)-3-cyano-2-oxo-1,2-dihydropyridin-1-yl]acetate (CAS 478080-39-6)
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- 2-(3-Amino-5-chloro-4-hydroxybenzyl)isoindoline-1,3-dione (CAS 696650-05-2)
- methyl 6-(4-chlorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 878124-87-9)
- 4-(1-Acetyl-1,4-dihydropyridin-4-yl)-2-phenyloxazol-5(4H)-one (CAS 79305-12-7)
- 3-(4-Bromo-2-fluorophenyl)-2-chloro-1-propene (CAS 951894-13-6)
- Ethyl 2-cyano-3-methylbutanoate (CAS 3213-49-8)
- cis-1,1-Dimethylethyl N-[3-(2-methyl-1-oxopropyl)cyclobutyl]carbamate (CAS 2290827-44-8)
- Ethyl 2-(3-methoxy-4-nitro-1h-pyrazol-1-yl)acetate (CAS 514799-06-5)
- 5-(Chloromethyl)-1-methyl-3-(thiophen-2-yl)-1H-pyrazole (CAS 876316-96-0)
- n-Cyclopropyl-2-((4-methoxypyrimidin-2-yl)amino)acetamide (CAS 925550-69-2)
- (3-Bromo-4-fluorophenyl)(methyl)sulfane (CAS 1511032-71-5)
- N-(4-(Furan-2-yl)thiazol-2-yl)-2-(4-(trifluoromethoxy)phenyl)-2H-tetrazole-5-carboxamide (CAS 1396881-75-6)
- Peptide Impurity (CAS CATO-CPTD788810)
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