7-Chloro-3-(4-methoxyphenyl)quinazoline-2,4(1H,3H)-dione CAS 61680-18-0
| CAS No. | 61680-18-0 |
| Molecular Formula | C15H11ClN2O3 |
| Molecular Weight | 302.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 7-Chloro-3-(4-methoxyphenyl)quinazoline-2,4(1H,3H)-dione (CAS 61680-18-0), a certified reference material (molecular formula C15H11ClN2O3, MW 302.71 g/mol) for analytical method development and quality control.
The molecular framework of 7-Chloro-3-(4-methoxyphenyl)quinazoline-2,4(1H,3H)-dione (C15H11ClN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-3-(4-methoxyphenyl)quinazoline-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11ClN2O3 |
| Molecular Weight | 302.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-CHLORO-9-CYCLOPENTYL-7,7-DIFLUORO-8,9-DIHYDRO-5H-PYRIMIDO[4,5-B][1,4]DIAZEPIN-6(7H)-ONE (CAS 1062246-01-8)
- 2-((6-Chloro-2-phenyl-1H-benzo[d]imidazol-1-yl)oxy)acetic acid (CAS 338978-62-4)
- 2-(5-Chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetic acid (CAS 79759-53-8)
- 2-Chloro-3-(5-(methoxymethyl)furan-2-yl)naphthalene-1,4-dione (CAS 65679-85-8)
- 2-Chloro-9-(4,4-difluorocyclohexyl)-7-methyl-7,9-dihydro-8H-purin-8-one (CAS 2408842-49-7)
- 3-chloro-5-ethoxy-4-(2-ethoxy-2-oxoethoxy)benZoic acid (CAS 866768-15-2)
- 6-Chloro-3-hydroxy-2-(2-methoxyphenyl)quinazolin-4(3H)-one (CAS 338412-69-4)
- 7-Chloro-3-hydroxy-2-(2-methoxyphenyl)-3,4-dihydroquinazolin-4-one (CAS 338412-70-7)
Recommended Standards
- Methyl 2-[4-(4-chlorophenyl)-3-cyano-2-oxo-1,2-dihydropyridin-1-yl]acetate (CAS 478080-39-6)
- Methyl 3-chloro-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepine-7-carboxylate (CAS 755034-06-1)
- methyl 6-(4-chlorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 878124-87-9)
- Ethacridine Lactate Impurity 12 (CAS 20304-69-2)
- (S)-6,7-Dihydro-5H-cyclopenta[c]pyridin-5-ol (CAS 2096419-37-1)
- 2-Methylpropene-1,1-d2 (gas) (CAS 1560-59-4)
- 1-(5-(4-Methoxyphenyl)thiophen-2-yl)ethan-1-amine (CAS 1369386-79-7)
- 1-(3-Methoxy-4-methylphenyl)cyclopropanecarboxylic Acid (CAS 926209-30-5)
- Crizotinib Impurity 54 (CAS CATO-C4X-102554)
- (1R,2R)-cis-1-(Chloromethyl)-2-methylcyclopropane (CAS 10524-04-6)
- Ethyl 6-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 111185-65-0)
- 1-(3-(Difluoromethyl)-1-methyl-1H-pyrazol-4-yl)ethan-1-one (CAS 1814920-62-1)
- 4-Bromo-2-(3-methoxyphenyl)pyridazin-3(2h)-one (CAS 2090778-60-0)
- Semaglutide impurity 29 (CAS 110990-08-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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