4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl 4-methylbenzene-1-sulfonate CAS 338416-37-8
| CAS No. | 338416-37-8 |
| Molecular Formula | C20H15ClF3NO3S |
| Molecular Weight | 441.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl 4-methylbenzene-1-sulfonate (CAS 338416-37-8), molecular formula C20H15ClF3NO3S and molecular weight 441.85 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl 4-methylbenzene-1-sulfonate (C20H15ClF3NO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl 4-methylbenzene-1-sulfonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H15ClF3NO3S |
| Molecular Weight | 441.85 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related chloro Standards
- (E)-2-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}-N-(4-methylphenyl)ethene-1-sulfonamide (CAS 478080-66-9)
- 2-(2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)acetyl)-N-methylhydrazine-1-carbothioamide (CAS 306977-97-9)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618414-35-0)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573695-56-4)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573950-78-4)
- 4-Chloro-N'-(1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonyl)benzenesulfonohydrazide (CAS 477709-82-3)
- Ethyl 2-((2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-6-methylpyrimidin-4-yl)sulfonyl)acetate (CAS 1823182-28-0)
- (Z)-3-(5-chloro-1,3-diphenyl-1H-pyrazol-4-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile (CAS 956189-95-0)
Recommended Standards
- [1-Methyl-5-(phenylsulfanyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl N-(4-chlorophenyl)carbamate (CAS 318239-63-3)
- 5-[(2-Chlorophenyl)sulfanyl]-N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321553-40-6)
- GW 848687X (CAS 612831-24-0)
- 5-((4-Chlorophenyl)thio)-N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 158712-45-9)
- 2-(2-Oxocyclohexyl)acetonitrile (CAS 42185-27-3)
- 3-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-ylmethyl]-benzoic acid methyl ester (CAS 1404431-51-1)
- 1-((2,5-Dibromophenyl)sulfonyl)azepane (CAS 457961-20-5)
- 4-Ethylaminopent-3-en-2-one, 95% (CAS 50967-59-4)
- 2-(1-Methoxyethyl)oxazole-4-carboxylic acid (CAS 1566576-18-8)
- Tert-butyl (6Z)-6-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene]-2-azaspiro[3.4]octane-2-carboxylate (CAS 2763648-54-8)
- Dicloran (CAS 99-30-9)
- Cadmium oxide (CAS 1306-19-0)
- 3-(4-Hydroxyphenyl)-3-phenylbutan-2-one (CAS 3155-04-2)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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