2-(2,4-Difluorophenoxy)-1-methyl-1H-indole-3-carbaldehyde CAS 338416-86-7
| CAS No. | 338416-86-7 |
| Molecular Formula | C16H11F2NO2 |
| Molecular Weight | 287.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(2,4-Difluorophenoxy)-1-methyl-1H-indole-3-carbaldehyde (CAS 338416-86-7), a certified reference material (molecular formula C16H11F2NO2, MW 287.26 g/mol) for analytical method development and quality control.
2-(2,4-Difluorophenoxy)-1-methyl-1H-indole-3-carbaldehyde (C16H11F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2,4-Difluorophenoxy)-1-methyl-1H-indole-3-carbaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11F2NO2 |
| Molecular Weight | 287.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenoxy Standards
- 2-(2,4-Difluorophenoxy)-1-methyl-1H-indole-3-carbaldehyde (CAS 773872-28-9)
- 3-(2,4-Difluorophenoxy)-1-methylquinoxalin-2(1H)-one (CAS 338774-59-7)
- 2-(2,4-Difluorophenoxy)-5-(trifluoromethyl)aniline (CAS 183110-79-4)
- 2-(3,4-Difluorophenoxy)-5-(trifluoromethyl)aniline (CAS 946728-17-2)
- 4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)aniline (CAS 946698-40-4)
- 4-(2,4-Difluorophenoxy)-3-(trifluoromethyl)aniline (CAS 946697-82-1)
- 4-(3,4-Difluorophenoxy)-2-(trifluoromethyl)aniline (CAS 946663-37-2)
- 4-(3,4-Difluorophenoxy)-3-(trifluoromethyl)aniline (CAS 946662-97-1)
Recommended Standards
- 2-(1H-Benzo[d]imidazol-1-yl)-N-(3,4-difluorophenyl)acetamide (CAS 733791-01-0)
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- 2-(3-(Trifluoromethyl)benzyl)thiazole-4-carboxylic acid (CAS 478030-66-9)
- 2-((Tert-butoxycarbonyl)amino)-2-(3,4-difluorophenyl)acetic acid (CAS 672961-72-7)
- 1,1',1''-((2,4,6-Triethylbenzene-1,3,5-triyl)tris(methylene))tris(3,5-dimethyl-1H-pyrazole) (CAS 250581-65-8)
- 1-Ethylpiperidine-2-carboxylic acid (CAS 69081-83-0)
- 5-Hydroxybenzofuran-2-carbaldehyde (CAS 64418-91-3)
- 1-Hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (CAS 103986-80-7)
- 1,1'-(6-Bromopyridine-2,4-diyl)bis(ethan-1-one) (CAS 1393545-43-1)
- 2-Amino-3-methylphenyl trifluoromethanesulfonate (CAS 1589523-29-4)
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- 5-Bromo-2-(phenylmethoxy)benzonitrile (CAS 835898-37-8)
- 3-(4-chlorophenyl)-2,1-benzisoxazole-5-carbonitrile (CAS 344276-72-8)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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