2-(3,4-Difluorophenoxy)-5-(trifluoromethyl)aniline CAS 946728-17-2
| CAS No. | 946728-17-2 |
| Molecular Formula | C13H8F5NO |
| Molecular Weight | 289.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3,4-Difluorophenoxy)-5-(trifluoromethyl)aniline (C13H8F5NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 2-(3,4-Difluorophenoxy)-5-(trifluoromethyl)aniline (CAS 946728-17-2), a certified reference material (molecular formula C13H8F5NO, MW 289.20 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(3,4-Difluorophenoxy)-5-(trifluoromethyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8F5NO |
| Molecular Weight | 289.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenoxy Standards
- 2-(2,4-Difluorophenoxy)-5-(trifluoromethyl)aniline (CAS 183110-79-4)
- 4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)aniline (CAS 946698-40-4)
- 4-(2,4-Difluorophenoxy)-3-(trifluoromethyl)aniline (CAS 946697-82-1)
- 4-(3,4-Difluorophenoxy)-2-(trifluoromethyl)aniline (CAS 946663-37-2)
- 4-(3,4-Difluorophenoxy)-3-(trifluoromethyl)aniline (CAS 946662-97-1)
- (S)-3-(2,4-Difluorophenoxy)-2-((ethoxycarbonyl)amino)propanoic acid (CAS 1184842-84-9)
- 3-(2,4-Difluorophenoxy)-1-methylquinoxalin-2(1H)-one (CAS 338774-59-7)
- 2-(2,4-Difluorophenoxy)-1-methyl-1H-indole-3-carbaldehyde (CAS 338416-86-7)
Recommended Standards
- 2-(2,6-Difluoro-4-(trifluoromethyl)phenoxy)aniline (CAS 2244085-17-2)
- 2,2'-(Adamantane-1,3-diyl)diacetyl chloride (CAS 31898-14-3)
- 2-(((Perfluorophenyl)amino)methyl)phenol (CAS 329779-37-5)
- 2,5-Di-tert-butyl-3,6-dichloro-2,5-cyclohexadiene-1,4-dione (CAS 33611-73-3)
- 1-(4-(4-Nitrophenyl)-1,4-diazepan-1-yl)ethan-1-one (CAS 892491-96-2)
- 5-Hydroxy-1H-indole-2-carboxylic Acid Ethyl Ester (CAS 24985-85-1)
- (1-Ethyl-1h-1,2,4-triazol-5-yl)methanesulfonyl chloride (CAS 1491579-97-5)
- 5-(Bromomethyl)nicotinonitrile hydrobromide (CAS 2089300-77-4)
- 4-(benzylsulfanyl)-3,5-dimethyl-1H-pyrazole (CAS 1461705-56-5)
- (6-(Methylsulfonyl)pyridin-3-yl)methanamine dihydrochloride (CAS 2126159-53-1)
- (S)-Methyl 2-amino-3-(4-vinylphenyl)propanoate (CAS 1212880-64-2)
- Flurbiprofen impurity 102 (CAS CATO-C4X-1444102)
- (5-Methyl-2-(trifluoromethyl)furan-3-yl)methanamine (CAS 306935-05-7)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
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