4-(4-Chlorophenyl)-5-((4-chlorophenyl)sulfonyl)pyrimidin-2-amine CAS 338417-69-9
| CAS No. | 338417-69-9 |
| Molecular Formula | C16H11Cl2N3O2S |
| Molecular Weight | 380.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(4-Chlorophenyl)-5-((4-chlorophenyl)sulfonyl)pyrimidin-2-amine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(4-Chlorophenyl)-5-((4-chlorophenyl)sulfonyl)pyrimidin-2-amine (CAS 338417-69-9), a certified reference material (molecular formula C16H11Cl2N3O2S, MW 380.25 g/mol) for analytical method development and quality control.
4-(4-Chlorophenyl)-5-((4-chlorophenyl)sulfonyl)pyrimidin-2-amine (C16H11Cl2N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11Cl2N3O2S |
| Molecular Weight | 380.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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- (E)-2-[5-(4-Chlorophenyl)-2-furyl]-N-(2-thienylmethyl)-1-ethenesulfonamide (CAS 339018-47-2)
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Recommended Standards
- 2-cyano-N-({[(2,4-dichlorobenzyl)oxy]imino}methyl)-3-(2-thienyl)acrylamide (CAS 338976-39-9)
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- 4-Iodo-N-(1-methyl-4-piperidinyl)benzenesulfonamide (CAS 866041-15-8)
- 1-[(3,4-Dichlorophenyl)methyl]-2-oxo-N-(1,3-thiazol-2-yl)-1,2-dihydropyridine-3-carboxamide (CAS 338782-87-9)
- 4-(2-Chloroethyl)-N-(2-methoxyethyl)benzenesulfonamide (CAS 1018334-05-8)
- 3-(4-Nitrophenyl)azetidine hydrochloride (CAS 7606-34-0)
- 2-Chloro-1-(2-((isopropyl(methyl)amino)methyl)pyrrolidin-1-yl)ethanone (CAS 1353958-64-1)
- Aurate(1-), tetrachloro-, hydrogen, monohydrate, (SP-4-1)- (CAS 635727-68-3)
- 4-Hydroxy-4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid (CAS 1520859-18-0)
- 4-(1,2,4-Oxadiazol-3-yl)benzaldehyde (CAS 545424-41-7)
- Methyl 2-iodo-3,3,3-trifluoropropanoate (CAS 666-93-3)
- 2-Methyl-1-(naphthalen-1-yl)propan-1-amine (CAS 93005-12-0)
- 1-(Thiophen-2-yl)cyclohexane-1-carboxylic acid (CAS 100058-72-8)
- SAMS Peptide (CAS 125911-68-4)
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