Methyl 2-iodo-3,3,3-trifluoropropanoate CAS 666-93-3
| CAS No. | 666-93-3 |
| Molecular Formula | C4H4F3IO2 |
| Molecular Weight | 267.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2-iodo-3,3,3-trifluoropropanoate.
Methyl 2-iodo-3,3,3-trifluoropropanoate (CAS 666-93-3) is a high-purity analytical reference standard with the molecular formula C4H4F3IO2 and a molecular weight of 267.97 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, Methyl 2-iodo-3,3,3-trifluoropropanoate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.97 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-iodo-3,3,3-trifluoropropanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H4F3IO2 |
| Molecular Weight | 267.97 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/I-containing |
Related Methyl Standards
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Recommended Standards
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- 1-((1-(3-Bromophenyl)ethyl)amino)-2-methylpropan-2-ol (CAS 1183050-84-1)
- Semaglutide impurity 29 (CAS 1188328-22-4)
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