2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-6-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine CAS 338417-84-8
| CAS No. | 338417-84-8 |
| Molecular Formula | C18H12Cl2FN5S |
| Molecular Weight | 420.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-6-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (C18H12Cl2FN5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-6-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338417-84-8), a certified reference material (molecular formula C18H12Cl2FN5S, MW 420.29 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H12Cl2FN5S |
| Molecular Weight | 420.29 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 3-Chloro-2-[(3,5-dibromo-1H-1,2,4-triazol-1-yl)methyl]-5-(trifluoromethyl)pyridine (CAS 1092346-47-8)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-1-yl)(2,4-dichlorophenyl)methanone (CAS 251096-68-1)
- 2-Chloro-1-[(2S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(tetrahydro-2H-pyran-2-yl)oxy]propyl]-4-nitro-1H-imidazole (CAS 943610-38-6)
- 4-((2-Chloro-6-fluorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde (CAS 693805-30-0)
- 4-((2-Chloro-4-fluorobenzyl)oxy)-3-iodobenzohydrazide (CAS 1706451-12-8)
- 2-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)-N,N-diphenylacetamide (CAS 1023798-42-6)
- N-(3-Chloro-2-methylphenyl)-2-((2-phenylquinazolin-4-yl)thio)acetamide (CAS 332914-46-2)
- 6-chloro-3-[3-[4-(2,3,5,6-tetradeuterio-4-fluorobenzoyl)piperidin-1-yl]propyl]-1H-benzimidazol-2-one (CAS 1794979-06-8)
Recommended Standards
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-6-(4-fluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338403-80-8)
- 3,4-Dichloro-N-(4,6-diphenylpyrimidin-2-yl)benzamide (CAS 820961-62-4)
- 2,2'-((6-(Bis(phosphonomethyl)amino)hexyl)azanediyl)diacetic acid (CAS 58534-59-1)
- Ethyl 2-(2-(1-(2,4-dichlorobenzamido)ethyl)-1H-benzo[d]imidazol-1-yl)acetate (CAS 866038-56-4)
- 2-Amino-N-(4-methoxyphenyl)benzo[d]thiazole-6-sulfonamide (CAS 1807739-99-6)
- 2-(Isoquinolin-7-yl)acetamide (CAS 1503424-83-6)
- (R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5,5-dimethylpyrrolidine-2-carboxylic acid (CAS 1310680-45-5)
- 2-(5-Amino-1H-benzo[d][1,2,3]triazol-1-yl)propanoic acid (CAS 1532930-48-5)
- Benzyl (S)-3-(dimethylamino)pyrrolidine-1-carboxylate (CAS 1217602-15-7)
- 2-[(5-Amino-2-pyridinyl)(ethyl)amino]-1-ethanol (CAS 1017221-30-5)
- 4-Amino-3-ethoxybenzoic acid (CAS 367501-31-3)
- (R)-5-(1-Aminoethyl)-2-fluoro-3-(trifluoromethyl)aniline hydrochloride (CAS 2654746-47-9)
- PACA (CAS 1431724-30-9)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com