2-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfanyl]-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}acetohydrazide CAS 338418-56-7
| CAS No. | 338418-56-7 |
| Molecular Formula | C16H14F3N5O2S2 |
| Molecular Weight | 429.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfanyl]-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}acetohydrazide (CAS 338418-56-7), molecular formula C16H14F3N5O2S2 and molecular weight 429.44 g/mol, is a CATO reference standard with documented purity and traceability.
2-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfanyl]-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}acetohydrazide (C16H14F3N5O2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfanyl]-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}acetohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14F3N5O2S2 |
| Molecular Weight | 429.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cyano Standards
- Ethyl 2-(2-((3-cyano-4,6-dimethylpyridin-2-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 333778-29-3)
- Ethyl 5-cyano-6-[(2,4-dichlorophenyl)sulfanyl]-2-phenylpyridine-3-carboxylate (CAS 860784-73-2)
- 4-Cyano-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl 3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylate (CAS 956825-58-4)
- 2-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfanyl]-N'-[2-(2,4-dichlorophenoxy)ethanimidoyl]acetohydrazide (CAS 338395-70-3)
- 2-((3-Cyano-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)-N-(3-cyanophenyl)acetamide (CAS 626228-76-0)
- Ethyl 5-cyano-2-phenyl-6-{[3-(trifluoromethyl)phenyl]sulfanyl}pyridine-3-carboxylate (CAS 306980-03-0)
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)thio)phenyl)-3-methoxybenzamide (CAS 477866-69-6)
- N-(4-Cyano[1,1-biphenyl]-4-yl)-N-[4-(3H-imidazo[4,5-β]pyridin-7-yl)phenyl] Urea (CAS 1361414-26-7)
Recommended Standards
- 2-((4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)methyl)-2,3-dihydroimidazo[1,2-c]quinazolin-5(1H)-one (CAS 306977-77-5)
- 2-Hydroxy-3-(1-(phenylsulfonyl)-1H-indol-3-yl)naphthalene-1,4-dione (CAS 918905-46-1)
- 3-(Thiophen-2-ylmethyl)-5-(1-((4-(trifluoromethyl)phenyl)sulfonyl)azetidin-3-yl)-1,2,4-oxadiazole (CAS 1351608-30-4)
- 5-(4-(4-Methylpiperazin-1-yl)phenyl)-N-(3-(trifluoromethyl)phenyl)-1H-pyrazole-1-carboxamide (CAS 321998-93-0)
- 1-(3,4-Dichlorobenzyl)-1H-pyrazol-4-amine (CAS 895929-62-1)
- 7-Methoxy-1-oxo-2h-isoquinoline-6-carbonitrile (CAS 2350323-59-8)
- 5-Bromo-4-methyl-2-(prop-1-en-2-yl)thiazole (CAS 1558007-96-7)
- 3-{3-tert-butyl-1-methyl-4-oxo-1H,4H-indeno[1,2-c]pyrazol-6-yl}-1-(2-methylphenyl)urea (CAS 1024523-14-5)
- PF 477736 (CAS 952021-60-2)
- Methyl 2-chloro-5-nitrobenzoate (CAS 6307-82-0)
- 3-(4-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-amine (CAS 1260886-71-2)
- 1-(3-((2-Hydroxyethyl)(isopropyl)amino)piperidin-1-yl)ethanone (CAS 1353948-33-0)
- Voglibose impurity 19 (CAS 114761-39-6)
- D-Val23-Tirzepatide (CAS CATO-CPTD788911)
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