4-(2,4-Dichlorobenzoyl)-1-methyl-N'-(2-phenoxyethanimidoyl)-1H-pyrrole-2-carbohydrazide CAS 338418-58-9
| CAS No. | 338418-58-9 |
| Molecular Formula | C21H18Cl2N4O3 |
| Molecular Weight | 445.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-(2,4-Dichlorobenzoyl)-1-methyl-N'-(2-phenoxyethanimidoyl)-1H-pyrrole-2-carbohydrazide (CAS 338418-58-9), a certified reference material (molecular formula C21H18Cl2N4O3, MW 445.30 g/mol) for analytical method development and quality control.
The molecular framework of 4-(2,4-Dichlorobenzoyl)-1-methyl-N'-(2-phenoxyethanimidoyl)-1H-pyrrole-2-carbohydrazide (C21H18Cl2N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-(2,4-Dichlorobenzoyl)-1-methyl-N'-(2-phenoxyethanimidoyl)-1H-pyrrole-2-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18Cl2N4O3 |
| Molecular Weight | 445.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichlorobenzoyl Standards
- 3-(2,4-Dichlorobenzoyl)-5-(3,4-dichlorobenzylidene)-2-thioxoimidazolidin-4-one (CAS 732288-03-8)
- 1-[4-(2,3-Dichlorobenzoyl)-1H-pyrrole-2-carbonyl]-4-(2-fluorophenyl)piperazine (CAS 477870-32-9)
- 8-Benzyl-4-(3,5-dichlorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-91-6)
- 8-Benzyl-4-(2,4-dichlorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-19-1)
- 8-Benzyl-4-(3,4-dichlorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-26-6)
- 4-(2,4-Dichlorobenzoyl)-N-dodecyl-1H-pyrrole-2-carboxamide (CAS 672949-68-7)
- Methyl 4-[4-(3,4-dichlorobenzoyl)piperazin-1-yl]-3-nitrobenzoate (CAS 341967-75-7)
- (E)-({4-[4-(2,4-dichlorobenzoyl)piperazin-1-yl]-3-nitrophenyl}methylidene)(methoxy)amine (CAS 383147-25-9)
Recommended Standards
- 1-(4-Bromobenzenesulfonyl)-N-(3,4-difluorophenyl)pyrrolidine-2-carboxamide (CAS 317377-76-7)
- 4-[(3,4-Dichlorophenyl)methoxy]-N'-[(1E)-(4-hydroxy-3-methoxyphenyl)methylidene]benzohydrazide (CAS 303987-41-9)
- (5-Bromopyridin-3-yl)(3-((3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone (CAS 1704537-68-7)
- N-(2,4-dichlorophenyl)-5-(4-methoxybenzyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-3-carboxamide (CAS 303986-77-8)
- [(1-Cyclopentylpyrrolidin-3-yl)methyl]amine (CAS 933714-21-7)
- 6-Amino-2-bromo-pyridin-3-ol (CAS 1187930-22-8)
- N-(3-Chloro-2-methylphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105207-28-0)
- 2-(Difluoromethyl)-5-iodo-3-methylpyridine-6-sulfonamide (CAS 1806950-13-9)
- 2-Iodo-5-methylbenzonitrile (CAS 42872-86-6)
- 2,4-Dinitrophenylhydrazine-d3 (CAS 259824-49-2)
- 2-Hydroxy-3,3-dimethylbicyclo[2.2.1]heptane-1-carboxylic acid (CAS 469-73-8)
- 6-Bromo-1-methyl-2(1H)-pyridone (CAS 873383-11-0)
- 3-Acetyl-5,5-dimethyldihydrofuran-2(3H)-one (CAS 7391-53-9)
- Semaglutide impurity 277 (CAS CATO-C4X-2226277)
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