1-Benzyl-3'-(3-(trifluoromethyl)phenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione CAS 338418-99-8
| CAS No. | 338418-99-8 |
| Molecular Formula | C24H17F3N2O2S |
| Molecular Weight | 454.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 454.46 g/mol gives 1-Benzyl-3'-(3-(trifluoromethyl)phenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-Benzyl-3'-(3-(trifluoromethyl)phenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 338418-99-8), molecular formula C24H17F3N2O2S and molecular weight 454.46 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Benzyl-3'-(3-(trifluoromethyl)phenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (C24H17F3N2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-Benzyl-3'-(3-(trifluoromethyl)phenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H17F3N2O2S |
| Molecular Weight | 454.46 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Benzyl Standards
- 3'-Phenyl-1-(3-(trifluoromethyl)benzyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 338418-93-2)
- 4-((2-Oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)-N-(3-(trifluoromethyl)benzyl)benzamide (CAS 339025-40-0)
- 4-[3,5-Bis(trifluoromethyl)benzoyl]-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326815-18-2)
- 3,3''-Bis(trifluoromethyl)-[1,1':4',1''-terphenyl]-4,4''-dicarboxylic acid (CAS 2308530-30-3)
- 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid (CAS 1076197-34-6)
- 1-Acetyl-5-[[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]sulfonyl]indoline (CAS 901260-40-0)
- 1-(3-(Trifluoromethyl)phenyl)-3-(4-(2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)phenyl)urea (CAS 1022634-82-7)
- 6-{[2-methyl-7-(trifluoromethyl)-2,3,4,5-tetrahydro-1,5-benzothiazepin-5-yl]sulfonyl}-2h-chromen-2-one (CAS 1147644-57-2)
Recommended Standards
- 1-(4-Bromophenyl)-3-(dodecylsulfanyl)pyrrolidine-2,5-dione (CAS 331461-21-3)
- 2-(2,4-Diphenylthiazol-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 339277-64-4)
- [(2R,3S,4R,5R)-5-[6-(6-aminohexylamino)purin-9-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate (CAS 38198-98-0)
- Raltegravir Impurity15 (CAS 519028-33-2)
- 2-Amino-N-(2-methoxyphenethyl)benzamide (CAS 527690-05-7)
- 1-Methyl-1H-imidazo[1,2-b]pyrazole (CAS 56728-16-6)
- 3-Oxo-7-(trifluoromethyl)-3,4-dihydroquinoxaline-2-carboxylic acid (CAS 219485-21-9)
- (5-Bromo-2-methylthiophen-3-yl)methanol (CAS 1492327-07-7)
- 3-(3,4-Dihydroisoquinolin-2(1H)-yl)-1,2,4-triazin-5(4H)-one (CAS 857491-98-6)
- 4-Ethynylbenzo-15-crown-5 (CAS 92710-94-6)
- 7-(Trifluoromethyl)quinazoline-2,4(1H,3H)-dione (CAS 3833-78-1)
- 3,6-Bis(prop-2-yn-1-yloxy)acridine-9(10H)-thione (CAS 122105-97-9)
- 3-Oxocyclobutyl Pivalate (CAS 1071194-23-4)
- TAT 14 Peptide (Nrf2 Activator III) (CAS 1362661-34-4)
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