Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenyl-1H-indole-2-carboxylate CAS 338748-77-9
| CAS No. | 338748-77-9 |
| Molecular Formula | C23H16ClF3N2O2 |
| Molecular Weight | 444.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenyl-1H-indole-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenyl-1H-indole-2-carboxylate (CAS 338748-77-9), molecular formula C23H16ClF3N2O2 and molecular weight 444.83 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenyl-1H-indole-2-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 444.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C23H16ClF3N2O2 |
| Molecular Weight | 444.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- (3Z)-3-{[(4-chlorophenyl)methoxy]imino}-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-2-one (CAS 477853-36-4)
- SAR-20347 (CAS 1450881-55-6)
- 4-(3-(Benzo[d][1,3]dioxol-5-yl)-1,2,4-oxadiazol-5-yl)-2-(3-chlorophenyl)phthalazin-1(2H)-one (CAS 1291862-60-6)
- 4,4',5,5'-Tetrakis(ethylthio)-2,2'-bi(1,3-dithiolylidene) (CAS 104515-79-9)
- 4-Ethoxy-2-methyl-5-(3-morpholinopropyl)-2H-benzo[b]pyridazino[4,3-e][1,4]oxazin-3(5H)-one (CAS 82413-00-1)
- 2-((3,4-Dichlorobenzyl)thio)-4,5-diphenyl-1H-imidazole (CAS 338412-84-3)
- 2-(Benzofuran-2-yl)-1H-imidazole hydrochloride (CAS 150985-44-7)
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- Bendamustine Impurity 40 (CAS CATO-C4X-127140)
- 2-(2,6-Difluorophenyl)-2,2-difluoroethan-1-ol (CAS 1581274-20-5)
- tert-butyl (2S)-2-(cyanomethyl)piperazine-1-carboxylate (CAS 1589565-36-5)
- 3-((tert-Butyldimethylsilyl)oxy)pyrrolidin-2-one (CAS 126645-95-2)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
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