3-[1-(3-Chloro-4-fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775516-32-9
| CAS No. | 1775516-32-9 |
| Molecular Formula | C22H22ClFN4O3 |
| Molecular Weight | 444.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-[1-(3-Chloro-4-fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-[1-(3-Chloro-4-fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775516-32-9), a certified reference material (molecular formula C22H22ClFN4O3, MW 444.89 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 3-[1-(3-Chloro-4-fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 444.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22ClFN4O3 |
| Molecular Weight | 444.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 3-[1-(2-Chloro-4-fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775365-93-9)
- 3-[1-(5-Chloro-2-fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775525-66-0)
- 3-[1-(4-Chloro-2-methoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775536-13-4)
- 2-{[2-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)-2-oxoethyl]sulfanyl}pyridin-1-ium-1-olate (CAS 339016-51-2)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5,6-diphenyl-1,2,4-triazine (CAS 866133-97-3)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(4-methoxyphenyl)-N',2-dimethylisoxazolidine-5-carbohydrazide (CAS 338774-93-9)
- Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenyl-1H-indole-2-carboxylate (CAS 338748-77-9)
- 3-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-(pyrimidin-2-ylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 321433-29-8)
Recommended Standards
- 3-{1-[2-(4-chlorophenoxy)acetyl]piperidin-4-yl}-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775524-46-3)
- Iridium, trichloro[1,1'-thiobis[butane]]- (CAS 67953-74-6)
- 5-Bromo-7-[trans-4-(tert-butyldimethylsilanyloxy)cyclohexyl]-2-chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS 1392804-15-7)
- 4-((4-Chlorophenyl)sulfonyl)-N-(4-ethoxyphenyl)-2-(furan-2-yl)oxazol-5-amine (CAS 862794-89-6)
- 3,3'-Disulfanediylbis(propan-1-amine) dihydrochloride (CAS 29205-72-9)
- (4-Chloro-5-methoxy-2-methylphenyl)boronic acid (CAS 2225174-69-4)
- 5-Amino-1-(2-hydroxyethoxy)-1H-pyrazol-4-ol (CAS 927417-40-1)
- 2-(3,5-Difluorophenoxy)aniline (CAS 1341725-06-1)
- 1,4-Oxazepane-6-carboxamide (CAS 1316223-37-6)
- 2-(4-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperazin-2-yl)acetic acid hydrochloride (CAS 1171909-95-7)
- 6-Chloro-9-hexadecyl-9H-purine (CAS 68180-15-4)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-one O-(4-methylbenzyl) oxime (CAS 250714-07-9)
- 1-(4-Aminophenyl)ethan-1-one hydrochloride (CAS 41784-08-1)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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