(Z)-3-(1-(2-(4-chlorophenyl)hydrazono)-2,2,2-trifluoroethyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrrole CAS 338749-40-9

Purity 97%+In StockPharmaceutical Standards
CAS No.338749-40-9
Molecular FormulaC27H20ClF6N3O2S
Molecular Weight599.98 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(Z)-3-(1-(2-(4-chlorophenyl)hydrazono)-2,2,2-trifluoroethyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrrole CAS 338749-40-9 chemical structure

Description

The occurrence of (Z)-3-(1-(2-(4-chlorophenyl)hydrazono)-2,2,2-trifluoroethyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrrole is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(Z)-3-(1-(2-(4-chlorophenyl)hydrazono)-2,2,2-trifluoroethyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrrole (CAS 338749-40-9), molecular formula C27H20ClF6N3O2S and molecular weight 599.98 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (Z)-3-(1-(2-(4-chlorophenyl)hydrazono)-2,2,2-trifluoroethyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrrole (C27H20ClF6N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC27H20ClF6N3O2S
Molecular Weight599.98 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)16.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms3
Sulfur Atoms1

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