2-(2-Naphthyloxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile CAS 338749-47-6

Purity 97%+In StockPharmaceutical Standards
CAS No.338749-47-6
Molecular FormulaC23H13F3N2O
Molecular Weight390.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-Naphthyloxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile CAS 338749-47-6 chemical structure

Description

2-(2-Naphthyloxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile (CAS 338749-47-6) is a high-purity analytical reference standard with the molecular formula C23H13F3N2O and a molecular weight of 390.36 g/mol.

Structurally, 2-(2-Naphthyloxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile (C23H13F3N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 390.36 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(2-Naphthyloxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC23H13F3N2O
Molecular Weight390.36 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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