4-(1-Naphthyloxy)-2-(trifluoromethyl)aniline CAS 212189-38-3
| CAS No. | 212189-38-3 |
| Molecular Formula | C17H12F3NO |
| Molecular Weight | 303.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(1-Naphthyloxy)-2-(trifluoromethyl)aniline (CAS 212189-38-3), molecular formula C17H12F3NO and molecular weight 303.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(1-Naphthyloxy)-2-(trifluoromethyl)aniline (C17H12F3NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 4-(1-Naphthyloxy)-2-(trifluoromethyl)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12F3NO |
| Molecular Weight | 303.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2017 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Naphthyloxy Standards
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Recommended Standards
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- 2-(Naphthalen-2-yloxy)-5-(trifluoromethyl)aniline (CAS 79567-22-9)
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