(3E)-1-Acetyl-4-benzyl-3-[(4-fluorophenyl)methylidene]piperazine-2,5-dione CAS 338750-20-2
| CAS No. | 338750-20-2 |
| Molecular Formula | C20H17FN2O3 |
| Molecular Weight | 352.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies (3E)-1-Acetyl-4-benzyl-3-[(4-fluorophenyl)methylidene]piperazine-2,5-dione (CAS 338750-20-2), a certified reference material (molecular formula C20H17FN2O3, MW 352.36 g/mol) for analytical method development and quality control.
The molecular framework of (3E)-1-Acetyl-4-benzyl-3-[(4-fluorophenyl)methylidene]piperazine-2,5-dione (C20H17FN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H17FN2O3 |
| Molecular Weight | 352.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3'-(Benzyloxy)-5'-fluoro-3-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1820618-85-6)
- 1-(3-Acetylphenyl)-3-(1-(4-fluorobenzyl)-1H-pyrazol-4-yl)urea (CAS 894502-73-9)
- 1-(2-((3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl)phenyl)-3-(2-fluorophenyl)urea (CAS 1797138-77-2)
- 2-(4-Fluorobenzenesulfonamido)-1,3-benzothiazole-6-carboxylic acid (CAS 929854-37-5)
- 1-Bromo-4,5-dichloro-2-nitrobenzene (CAS 93361-94-5)
- 1-(1-Bromopropyl)-4-(trifluoromethyl)benzene (CAS 139148-44-0)
- Methyl 7-methoxychromane-3-carboxylate (CAS 885271-74-9)
- 1-[4-(Pyridin-2-yl)piperazin-1-yl]-2-(thiophen-2-yl)ethan-1-one (CAS 433946-96-4)
- 4-(Furan-2-yl)-3-methoxybenzoic acid (CAS 1261925-34-1)
- (2,4,5-Trimethoxyphenyl)boronic acid (CAS 213698-56-7)
- 3-PHenyl-4-iodosydnone (CAS 13858-07-6)
- 7,7-dimethyl-2-azabicyclo[4.1.1]octane (CAS 1824544-73-1)
- (But-3-yn-1-yl)urea (CAS 1342824-24-1)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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