(6E)-1-Benzyl-6-(phenylmethylidene)piperazine-2,5-dione CAS 338750-19-9
| CAS No. | 338750-19-9 |
| Molecular Formula | C18H16N2O2 |
| Molecular Weight | 292.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 292.33 g/mol gives (6E)-1-Benzyl-6-(phenylmethylidene)piperazine-2,5-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(6E)-1-Benzyl-6-(phenylmethylidene)piperazine-2,5-dione (CAS 338750-19-9) is a high-purity analytical reference standard with the molecular formula C18H16N2O2 and a molecular weight of 292.33 g/mol.
The molecular framework of (6E)-1-Benzyl-6-(phenylmethylidene)piperazine-2,5-dione (C18H16N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (6E)-1-Benzyl-6-(phenylmethylidene)piperazine-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16N2O2 |
| Molecular Weight | 292.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
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