3-(4-Chlorophenyl)-1-methyl-4-(4-nitrobenzoyl)pyrrolidine CAS 338750-28-0
| CAS No. | 338750-28-0 |
| Molecular Formula | C18H17ClN2O3 |
| Molecular Weight | 344.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Chlorophenyl)-1-methyl-4-(4-nitrobenzoyl)pyrrolidine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(4-Chlorophenyl)-1-methyl-4-(4-nitrobenzoyl)pyrrolidine (CAS 338750-28-0), a certified reference material (molecular formula C18H17ClN2O3, MW 344.79 g/mol) for analytical method development and quality control.
The molecular framework of 3-(4-Chlorophenyl)-1-methyl-4-(4-nitrobenzoyl)pyrrolidine (C18H17ClN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN2O3 |
| Molecular Weight | 344.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 2-[4-(3-chlorophenyl)piperazine-1-carbonyl]benzoic acid (CAS 841270-53-9)
- Ethyl 4-{[(4-chlorophenyl)methyl]amino}-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 1221715-35-0)
- 7-(4-Chlorophenyl)-2-(o-tolyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 860611-21-8)
- 6-(2-Chlorophenyl)-2-(methylthio)pyrimido[5,4-e][1,2,4]triazolo[4,3-a]pyrimidin-5(6H)-one (CAS 1395026-89-7)
- (2E)-3-(4-Chlorophenyl)-1-[4-(4-fluorophenyl)piperazin-1-yl]prop-2-en-1-one (CAS 329080-13-9)
- 4'-((4-Chlorophenyl)sulfonyl)-[1,1'-biphenyl]-4-ol (CAS 30809-75-7)
- 1-(3-Chlorophenyl)-3-(1-(4-fluorobenzyl)-1H-pyrazol-3-yl)urea (CAS 1006199-61-6)
- 2-(4-Chlorophenyl)-N-((5-(4-fluorophenyl)isoxazol-3-yl)methyl)acetamide (CAS 953181-57-2)
Recommended Standards
- 2-Chloro-1-[3-(furan-2-yl)-7-(furan-2-ylmethylidene)-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl]ethan-1-one (CAS 380431-18-5)
- 7-Chloro-2-oxo-N-(quinolin-8-yl)octahydrobenzofuran-3-carboxamide (CAS 62737-31-9)
- 7-Chloro-N,N-diethyl-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 343375-47-3)
- 1,4-Diamino-2-butoxy-7-chloroanthracene-9,10-dione (CAS 88605-48-5)
- 2-Oxo-2-{4,7,7-trimethyl-3-oxobicyclo[2.2.1]heptan-2-yl}acetic acid (CAS 10277-34-6)
- 1-Iodoethyl decanoate (CAS 89296-74-2)
- Bis(prop-2-en-1-yl) oxalate (CAS 615-99-6)
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 578733-12-7)
- Ethyl 2,3-dichloro-4-(difluoromethoxy)phenylacetate (CAS 1807178-48-8)
- 3,5-Difluoro-3-(1,3-dioxolan-2-yl)benzophenone (CAS 898759-68-7)
- 3-Cyclopropylfuran (CAS 1563530-01-7)
- Propyl Gallate (CAS 121-79-9)
- 4-Methyl-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid (CAS 2377608-70-1)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
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