1-[(3,4-Dichlorophenyl)methyl]-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide CAS 338754-25-9
| CAS No. | 338754-25-9 |
| Molecular Formula | C14H12Cl2N2O2 |
| Molecular Weight | 311.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 311.16 g/mol gives 1-[(3,4-Dichlorophenyl)methyl]-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-[(3,4-Dichlorophenyl)methyl]-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338754-25-9), molecular formula C14H12Cl2N2O2 and molecular weight 311.16 g/mol, is a CATO reference standard with documented purity and traceability.
1-[(3,4-Dichlorophenyl)methyl]-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (C14H12Cl2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[(3,4-Dichlorophenyl)methyl]-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12Cl2N2O2 |
| Molecular Weight | 311.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- (3,5-Dichlorophenyl)(3,4-dimethoxyphenyl)methanone (CAS 116412-97-6)
- Methyl 3-(3,5-dichlorophenyl)-5-methoxybenzoate (CAS 1820739-86-3)
- (3,4-Dichlorophenyl)(3,4-dimethoxyphenyl)methanone (CAS 92436-56-1)
- (3,4-Dichlorophenyl)(3,5-dimethoxyphenyl)methanone (CAS 951892-36-7)
- 1-[(2,4-Dichlorophenyl)methyl]-N-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 242797-34-8)
- 1-[(2,6-Dichlorophenyl)methyl]-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338754-50-0)
- 2-[(3,4-dichlorophenyl)methoxy]-3-methoxybenzaldehyde (CAS 588714-48-1)
- 3-[(2,4-Dichlorophenyl)methoxy]-4-methoxybenzaldehyde (CAS 341942-08-3)
Recommended Standards
- 2-((2,6-Dichlorobenzyl)oxy)-3-methoxybenzaldehyde (CAS 588713-62-6)
- 2-[(2,4-Dichlorobenzyl)oxy]-3-methoxybenzaldehyde (CAS 433240-98-3)
- 1-(3,4-Dichlorobenzyl)-N-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 338781-22-9)
- 1-(2,4-Dichlorobenzyl)-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338977-56-3)
- 1,1,1-Trifluoro-N-[(11bS)-4-sulfido-2,6-bis[2,4,6-tris(1-methylethyl)phenyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]methanesulfonamide (CAS 1042671-81-7)
- 2-((2-Chlorophenyl)sulfinyl)-N-(4-(4-chlorophenyl)thiazol-2-yl)acetamide (CAS 338959-66-3)
- 2-Methoxy-5-(4-nitrobenzoyl)benzene-1-sulfonyl chloride (CAS 820245-86-1)
- 2-Bromo-N1-(tert-butyl)benzene-1,4-diamine (CAS 1249234-21-6)
- 2,2-Dimethyl-3-sulfanylpropan-1-ol (CAS 15718-66-8)
- Methyl 3-(4-amino-1h-pyrazol-1-yl)-2,2-dimethylpropanoate (CAS 1522384-29-7)
- N-(5-Chloro-2,4-dihydroxyphenyl)-1-phenylcyclobutane-1-carboxamide (CAS 1436798-56-9)
- Apremilast Impurity 24 (CAS 2487573-01-1)
- 2-Bromo-4-nitroanisole (CAS 5197-28-4)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com