Apremilast Impurity 24 CAS 2487573-01-1
| CAS No. | 2487573-01-1 |
| Molecular Formula | C23H26N2O8S |
| Molecular Weight | 490.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Apremilast Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Apremilast Impurity 24 (CAS 2487573-01-1, C23H26N2O8S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C23H26N2O8S, Apremilast Impurity 24 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 490.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H26N2O8S |
| Molecular Weight | 490.53 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 124 (CAS 2741194-01-2)
- Apremilast Impurity 53 (CAS CATO-C4X-100953)
- Apremilast Impurity 6 (CAS 1809170-71-5)
- Apremilast Impurity 7 (CAS 2096492-41-8)
- Apremilast Impurity 115 (CAS 1384814-94-1)
- Apremilast Impurity 32 (CAS CATO-C4X-100932)
- Apremilast Impurity 44 (CAS 2096492-44-1)
- Apremilast Impurity 83 (CAS 2096492-43-0)
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