1-(3-Chlorobenzyl)-3-(4-methylpiperazine-1-carbonyl)pyridin-2(1H)-one CAS 338754-96-4
| CAS No. | 338754-96-4 |
| Molecular Formula | C18H20ClN3O2 |
| Molecular Weight | 345.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(3-Chlorobenzyl)-3-(4-methylpiperazine-1-carbonyl)pyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(3-Chlorobenzyl)-3-(4-methylpiperazine-1-carbonyl)pyridin-2(1H)-one (CAS 338754-96-4) is a high-purity analytical reference standard with the molecular formula C18H20ClN3O2 and a molecular weight of 345.82 g/mol.
The molecular framework of 1-(3-Chlorobenzyl)-3-(4-methylpiperazine-1-carbonyl)pyridin-2(1H)-one (C18H20ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H20ClN3O2 |
| Molecular Weight | 345.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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- Methyl 4-((3-chlorobenzyl)oxy)-6-fluoroquinoline-2-carboxylate (CAS 1357936-14-1)
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- (E)-3-((4-chlorobenzyl)amino)-1-(2,5-dichlorothiophen-3-yl)prop-2-en-1-one (CAS 478245-96-4)
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Recommended Standards
- (4-(4-Aminophenyl)piperazin-1-yl)(5-chloro-2-methoxyphenyl)methanone (CAS 892693-46-8)
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- (3Z)-4-[(3-Chloro-2-methylphenyl)amino]-3-(3,4-dimethoxyphenyl)but-3-en-2-one (CAS 339017-39-9)
- 1-[(4-Chlorophenyl)methyl]-5-(4-methylpiperazine-1-carbonyl)-1,2-dihydropyridin-2-one (CAS 338783-47-4)
- Ethyl 6-chloropyrazolo[1,5-a]pyridine-3-carboxylate (CAS 55899-28-0)
- 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (CAS 994-36-5)
- (S)-N-((3,5-Dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl)-1-tosylpyrrolidine-2-carboxamide (CAS 957012-34-9)
- 5-(2-Chlorobenzylidene)-2-thioxothiazolidin-4-one (CAS 6318-36-1)
- 6-Chloro-4-methyl-5-azaindole (CAS 1352397-22-8)
- 2-((4-Chlorophenyl)sulfinyl)-4,6-dimethyl-3-(methylsulfonyl)pyridine (CAS 339016-99-8)
- 2-amino-1-[4-(propan-2-yloxy)phenyl]ethan-1-ol (CAS 1181405-27-5)
- 5-Bromo-3-cyclopropylisoxazole (CAS 1263378-59-1)
- Docosyl 2,3-dihydroxybenzoate (CAS 1238837-50-7)
- Liraglutide-d8 Tritrifluoroacetate (CAS CATO-C4X-199223)
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