(E)-1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-5-(3-(4-chlorophenyl)acryloyl)pyrimidine-2,4(1H,3H)-dione CAS 338770-10-8
| CAS No. | 338770-10-8 |
| Molecular Formula | C20H13Cl2F3N4O3 |
| Molecular Weight | 485.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(E)-1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-5-(3-(4-chlorophenyl)acryloyl)pyrimidine-2,4(1H,3H)-dione (CAS 338770-10-8) is a high-purity analytical reference standard with the molecular formula C20H13Cl2F3N4O3 and a molecular weight of 485.24 g/mol.
Based on its molecular formula C20H13Cl2F3N4O3, (E)-1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-5-(3-(4-chlorophenyl)acryloyl)pyrimidine-2,4(1H,3H)-dione contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 485.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H13Cl2F3N4O3 |
| Molecular Weight | 485.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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- Semaglutide238 (CAS CATO-C4X-2226238)
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