Nilotinib Iodo Impurity CAS 926922-18-1

Description

Compared with other compounds in its class, the molecular weight of 485.24 g/mol gives Nilotinib Iodo Impurity distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Nilotinib Iodo Impurity (CAS 926922-18-1), molecular formula C19H15F3IN3O and molecular weight 485.24 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Nilotinib Iodo Impurity (C19H15F3IN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Nilotinib Iodo Impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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