Ethyl 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate CAS 321522-13-8
| CAS No. | 321522-13-8 |
| Molecular Formula | C25H18ClF3N4O6 |
| Molecular Weight | 562.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate.
Ethyl 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate (CAS 321522-13-8), molecular formula C25H18ClF3N4O6 and molecular weight 562.88 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate (C25H18ClF3N4O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 562.88 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H18ClF3N4O6 |
| Molecular Weight | 562.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Ethyl Standards
- 3-Chloro-2-(4-{[3-(2-phenyl-1,3-thiazol-5-yl)-1H-pyrazol-1-yl]sulfonyl}phenoxy)-5-(trifluoromethyl)pyridine (CAS 318255-89-9)
- 4-[[6-Chloro-3-[N'-(2-chloro-3-fluorophenyl)ureido]-2-hydroxyphenyl]sulfonyl]piperazine-1-carboxylic (CAS 688763-67-9)
- 1-Des(3-chloro-2-pyridinyl)-1-(3-chloro-5-bromo-2-pyridinyl)chlorantraniliprole (CAS 500011-53-0)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-methyl-5-[(2E)-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 338770-35-7)
- Methyl 6-chloro-1-naphthoate (CAS 5471-30-7)
- 3-Chloro-2-[(Z)-2-(1-{3-[(4-chlorobenzenesulfonyl)methyl]-4-nitrophenyl}ethylidene)-1-methylhydrazin-1-yl]-5-(trifluoromethyl)pyridine (CAS 339016-36-3)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1H-pyrrole-2-carboxamide (CAS 338397-67-4)
- N-(3-chloro-4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-carboxamide (CAS 338397-72-1)
Recommended Standards
- 1,4-Dioxo-1,4-bis(tridecyloxy)butane-2-sulfonic acid (CAS 18271-58-4)
- (S)-(2-Amino-5-methoxy-4-((triisopropylsilyl)oxy)phenyl)(6-(((tert-butyldimethylsilyl)oxy)methyl)-5-azaspiro[2.4]heptan-5-yl)methanone (CAS 2305842-47-9)
- 2,5-Bis(dodecyloxy)terephthalohydrazide (CAS 165898-16-8)
- Dapagliflozin Impurity 179 (CAS CATO-C4X-1138179)
- 2-Methoxy-3-thenoylpyridine (CAS 332134-11-9)
- Indoline-5-boronic acid pinacol ester, 97% (CAS 1062174-44-0)
- 2,4-Dibutoxyphenylboronic Acid (CAS 870778-89-5)
- But-3-en-1-ylcyclohexane (CAS 4569-36-2)
- 2-(1H-Pyrrol-2-yl)thiazole (CAS 295311-94-3)
- 6-(4-Chlorophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione (CAS 37458-38-1)
- Benzyl 3-bromo-1H-pyrrole-2-carboxylate (CAS 2387596-41-8)
- [3-(benzyloxy)oxetan-3-yl]methanol (CAS 1620017-07-3)
- 3-Methyl-1H-pyrazol-4-amine dihydrochloride (CAS 854698-16-1)
- Peptide 438 (CAS CATO-CPTD788438)
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