(E)-2-(3-((3,5-bis(trifluoromethyl)phenyl)amino)-1-(dimethylamino)allylidene)malononitrile CAS 338773-54-9
| CAS No. | 338773-54-9 |
| Molecular Formula | C16H12F6N4 |
| Molecular Weight | 374.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 374.28 g/mol gives (E)-2-(3-((3,5-bis(trifluoromethyl)phenyl)amino)-1-(dimethylamino)allylidene)malononitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (E)-2-(3-((3,5-bis(trifluoromethyl)phenyl)amino)-1-(dimethylamino)allylidene)malononitrile (CAS 338773-54-9), a certified reference material (molecular formula C16H12F6N4, MW 374.28 g/mol) for analytical method development and quality control.
(E)-2-(3-((3,5-bis(trifluoromethyl)phenyl)amino)-1-(dimethylamino)allylidene)malononitrile (C16H12F6N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12F6N4 |
| Molecular Weight | 374.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- (2E)-3-(4-Chlorophenyl)-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one (CAS 95793-51-4)
- 1 4-Bis(trifluoromethyl)-1 4-diphenyl-2& (CAS 247170-26-9)
- N-(4-Bromophenyl)-N-phenylnaphthalen-2-amine (CAS 204065-88-3)
- 2-{[3,5-bis(trifluoromethyl)phenyl]amino}-4-(dimethylamino)pyridine-3-carbonitrile (CAS 338773-84-5)
- 5-Bromo-3-((tert-butoxycarbonyl)amino)thiophene-2-carboxylic acid (CAS 494833-77-1)
- N-[(2E)-3-(2-Ethoxyphenyl)prop-2-enoyl]glycine (CAS 899205-17-5)
- 2-chloro-4-(chloromethyl)thiophene (CAS 73919-91-2)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(2,6-dichlorophenyl)acetonitrile (CAS 338407-06-0)
- 2-Azabicyclo[3.1.0]Hexane-3-carboxamide (CAS 1779416-42-0)
- 3-Methylindole-5-carbonitrile (CAS 3613-06-7)
- 5,5-Dimethyl-2-(2-oxo-2-phenylethyl)cyclohexane-1,3-dione (CAS 37456-51-2)
- 3-Cyclopropoxy-2-methoxyisonicotinamide (CAS 1243470-68-9)
- 5-(4-Carboxyphenyl)picolinic acid (CAS 1261898-79-6)
- (β-Asp5)-Delta-Sleep Inducing Peptide (CAS 82602-88-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com