6-Hydroxy-1-methyl-2-oxo-N-[4-(trifluoromethoxy)phenyl]-1,2-dihydropyrimidine-4-carboxamide CAS 338774-80-4
| CAS No. | 338774-80-4 |
| Molecular Formula | C13H10F3N3O4 |
| Molecular Weight | 329.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Hydroxy-1-methyl-2-oxo-N-[4-(trifluoromethoxy)phenyl]-1,2-dihydropyrimidine-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 6-Hydroxy-1-methyl-2-oxo-N-[4-(trifluoromethoxy)phenyl]-1,2-dihydropyrimidine-4-carboxamide (CAS 338774-80-4), a certified reference material (molecular formula C13H10F3N3O4, MW 329.23 g/mol) for analytical method development and quality control.
6-Hydroxy-1-methyl-2-oxo-N-[4-(trifluoromethoxy)phenyl]-1,2-dihydropyrimidine-4-carboxamide (C13H10F3N3O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H10F3N3O4 |
| Molecular Weight | 329.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 3-(Methylamino)-4-nitro-N-(3-(trifluoromethyl)phenyl)-1H-pyrazole-1-carboxamide (CAS 318517-36-1)
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- tert-Butyl (3-amino-1-(4-bromophenyl)propyl)carbamate (CAS 898404-74-5)
- (3Z)-3-(4-Chlorobenzenesulfonyl)-4-[(4-fluorophenyl)amino]but-3-en-2-one (CAS 1025680-73-2)
- 2-(Dimethylamino)-5-ethylphenol (CAS 1243453-70-4)
- 5,6-Difluoro-2,1,3-benzothiadiazole (CAS 1293389-28-2)
- 3-Chloro-2-(difluoromethyl)pyridine (CAS 1805301-63-6)
- 5-Methoxy-2-methyl-1,4-naphthoquinone (CAS 22266-99-5)
- 1-(4-(2-Methoxyphenyl)-3-oxo-3,4-dihydropyrazin-2-yl)piperidine-4-carboxylic acid (CAS 1713174-92-5)
- 3-Amino-3-(5-bromo-2-methoxyphenyl)propan-1-ol (CAS 1247159-59-6)
- 4-(Dimethylamino)butanoyl chloride hydrochloride (CAS 98827-32-8)
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-({[3-(trifluoromethyl)phenyl]methoxy}amino)methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 321432-34-2)
- Anorexigenic Peptide (CAS 69275-10-1)
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