1-Methyl-2,6-dioxo-N-(2-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide CAS 338774-81-5
| CAS No. | 338774-81-5 |
| Molecular Formula | C13H10F3N3O3 |
| Molecular Weight | 313.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Methyl-2,6-dioxo-N-(2-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-Methyl-2,6-dioxo-N-(2-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338774-81-5), a certified reference material (molecular formula C13H10F3N3O3, MW 313.23 g/mol) for analytical method development and quality control.
1-Methyl-2,6-dioxo-N-(2-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (C13H10F3N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Methyl-2,6-dioxo-N-(2-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10F3N3O3 |
| Molecular Weight | 313.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 1-Methyl-2,6-dioxo-N-(3-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 861208-47-1)
- 1-Methyl-2,6-dioxo-N-(4-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338774-76-8)
- ((2,4-Dioxo-2,3,4,5-tetrahydro-1h-benzo[b][1,4]diazepin-7-yl)sulfonyl)glycine (CAS 923718-70-1)
- 3-{[(2,3-Dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)-sulfonyl]amino}propanoic acid (CAS 939746-10-8)
- N-(2,5-dioxo-5,6,7,8-tetrahydro-2H-chromen-3-yl)-4-methoxybenzamide (CAS 338404-99-2)
- 3-(1,1-Dioxo-1lambda~6~,4-thiazinan-4-yl)-3-(4-methoxyphenyl)propanoic acid (CAS 439096-86-3)
- 3-Benzyl-2,4-dioxo-3-azabicyclo[3.2.0]heptane-6-sulfonyl chloride (CAS 2090164-52-4)
- 2-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-(3-hydroxypropyl)acetamide (CAS 300815-66-1)
Recommended Standards
- 11-(Bromomethyl)-12-methyl-9,10-dihydro-9,10-ethanoanthracene (CAS 58240-61-2)
- 1-(4-Methoxyphenoxy)-2-nitro-4-(trifluoromethyl)benzene (CAS 1996-69-6)
- 1-(4-(4-Bromophenoxy)butyl)-4-methylpiperazine (CAS 93699-37-7)
- 2-((4-Bromophenyl)thio)-1-(thiophen-2-yl)ethan-1-one (CAS 380169-17-5)
- 2-Methyl-3,5,6,7,8,9-hexahydro-4H-pyrimido[4,5-d]azepin-4-one (CAS 391953-90-5)
- (R)-5-amino-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one (CAS 957130-49-3)
- m-toluenesulfonyl chloride (CAS 1899-93-0)
- 5-Chloro-1H-pyrazole (CAS 934758-92-6)
- 2-(4-Bromo-5-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1806771-45-8)
- 3-(2-Methylphenoxy)azetidine (CAS 954222-84-5)
- tert-Butyl 7-methyl-4,5-dihydro-3H-spiro[benzo[b][1,4]oxazepine-2,4'-piperidine]-1'-carboxylate (CAS 1956377-61-9)
- (cis-6-Methylpiperidin-3-yl)methanol hydrochloride (CAS 2007920-93-4)
- Tert-butyl (S)-3-mercaptopiperidine-1-carboxylate (CAS 610285-62-6)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
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