(7-Chloro-2,3-dihydro-4H-benzo[b][1,4]thiazin-4-yl)(4-chlorophenyl)methanone CAS 338778-04-4

Purity 97%+In StockPharmaceutical Standards
CAS No.338778-04-4
Molecular FormulaC15H11Cl2NOS
Molecular Weight324.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(7-Chloro-2,3-dihydro-4H-benzo[b][1,4]thiazin-4-yl)(4-chlorophenyl)methanone CAS 338778-04-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(7-Chloro-2,3-dihydro-4H-benzo[b][1,4]thiazin-4-yl)(4-chlorophenyl)methanone (CAS 338778-04-4), molecular formula C15H11Cl2NOS and molecular weight 324.22 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (7-Chloro-2,3-dihydro-4H-benzo[b][1,4]thiazin-4-yl)(4-chlorophenyl)methanone (C15H11Cl2NOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), (7-Chloro-2,3-dihydro-4H-benzo[b][1,4]thiazin-4-yl)(4-chlorophenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H11Cl2NOS
Molecular Weight324.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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