2-Chloro-N-(4-chlorobenzo[d]thiazol-2-yl)nicotinamide CAS 85678-88-2
| CAS No. | 85678-88-2 |
| Molecular Formula | C13H7Cl2N3OS |
| Molecular Weight | 324.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chloro-N-(4-chlorobenzo[d]thiazol-2-yl)nicotinamide (CAS 85678-88-2) is a high-purity analytical reference standard with the molecular formula C13H7Cl2N3OS and a molecular weight of 324.19 g/mol.
The molecular framework of 2-Chloro-N-(4-chlorobenzo[d]thiazol-2-yl)nicotinamide (C13H7Cl2N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-Chloro-N-(4-chlorobenzo[d]thiazol-2-yl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H7Cl2N3OS |
| Molecular Weight | 324.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 3-CARBOXY-5-CHLOROANISOLE 3-chloro-5-methoxybenzoic acid 5-CHLORO-M-ANISIC ACID 82477-67-6 AS06305 (CAS 82477-67-6)
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