N-(4-chlorophenyl)-7-fluoro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide CAS 338778-19-1
| CAS No. | 338778-19-1 |
| Molecular Formula | C20H12ClFN2O3 |
| Molecular Weight | 382.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, N-(4-chlorophenyl)-7-fluoro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (C20H12ClFN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 382.77 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
N-(4-chlorophenyl)-7-fluoro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 338778-19-1) is a high-purity analytical reference standard with the molecular formula C20H12ClFN2O3 and a molecular weight of 382.77 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H12ClFN2O3 |
| Molecular Weight | 382.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 5-(3-(2-Chlorophenyl)-5-methylisoxazol-4-yl)-3-(4-nitrophenyl)-1,2,4-oxadiazole (CAS 337932-16-8)
- 2-(3-(4-Chlorophenyl)-5,9-dimethyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)acetic acid (CAS 664366-16-9)
- 2-(4-Chlorophenyl)-N-(3-(trifluoromethyl)phenyl)thiazole-4-carboxamide (CAS 303998-34-7)
- 3-(2-Chlorophenyl)-4-((2-(trifluoromethyl)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-06-7)
- 3-(2-Chlorophenyl)-4-((4-(trifluoromethyl)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-47-6)
- 3-(3-(4-Chlorophenyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid (CAS 777857-52-0)
- 3-(3-Chlorophenyl)-4-((2-(trifluoromethyl)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-86-3)
- 3-(3-Chlorophenyl)-4-((4-(trifluoromethyl)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-35-5)
Recommended Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(2,6-dimethylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860789-14-6)
- BMS-986260 (CAS 2001559-19-7)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-morpholino-2-(pyridin-4-yl)acetonitrile (CAS 339099-85-3)
- Methyltrioctylsilane (CAS 3510-72-3)
- 3-Amino-6-methyl-5-nitro-1,2-dihydropyridin-2-one (CAS 85216-58-6)
- Isobutyl 2-ethylhexanoate (CAS 7434-89-1)
- Tri-t-butylphosphonium trifluoromethanesulfonate (CAS 1106696-25-6)
- 3-(Benzo[b]thiophen-3-yl)-2,2-dimethylpropan-1-ol (CAS 1496256-61-1)
- 2-(2-Benzylphenoxy)ethanamine hydrochloride (CAS 10429-44-4)
- 3-Hydrazinylpyridazine (CAS 40972-16-5)
- Methyl 1-((2-nitrophenyl)sulfonyl)piperidine-2-carboxylate (CAS 1040236-68-7)
- (2-((Difluoromethyl)thio)phenyl)(4-((1-phenyl-1H-tetrazol-5-yl)methyl)piperazin-1-yl)methanone (CAS 1049454-15-0)
- 2-Amino-3-(4-fluoro-3-(trifluoromethyl)phenyl)propanoic acid (CAS 1260004-58-7)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com